Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.42 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19774297 | 0.78 | MTNR1A (0.47) | MTNR1ASMYD3NPC1MAPK13MAPK12 | |
| SCHEMBL5066 | 0.75 | MTNR1A (0.42) | MTNR1ASMYD3NPC1MAPK13MAPK12 | |
| SCHEMBL424121 | 0.75 | MTNR1A (0.45) | MTNR1ASMYD3NPC1MAPK13MAPK12 | |
| SCHEMBL2295990 | 0.75 | MTNR1A (0.42) | MTNR1ASMYD3NPC1MAPK13MAPK12 | |
| SCHEMBL2697405 | 0.75 | MTNR1A (0.45) | MTNR1ASMYD3NPC1MAPK13MAPK12 | |
| SCHEMBL483233 | 0.75 | SMYD3 (0.48) | MTNR1ASMYD3NPC1MAPK13MAPK12 | |
| SCHEMBL13305784 | 0.75 | MTNR1A (0.45) | MTNR1ASMYD3NPC1MAPK13MAPK12 | |
| SCHEMBL4130897 | 0.75 | MTNR1A (0.45) | MTNR1ASMYD3NPC1MAPK13MAPK12 | |
| SCHEMBL6575709 | 0.75 | MTNR1A (0.45) | MTNR1ASMYD3NPC1MAPK13MAPK12 | |
| SCHEMBL1754232 | 0.75 | MTNR1A (0.45) | MTNR1ASMYD3NPC1MAPK13MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0796270-A2 | PEPTIDE COMPOUNDS FOR PREVENTION AND/OR TREATMENT OF NO-MEDIATED DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-24 | — | — | EP | claimed |