Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.47 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.43 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.43 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4832972 | 0.98 | LOXL2 (0.51) | LOXL2EPHX2TSHRCYP4A11CYP4F2 | |
| SCHEMBL22921868 | 0.91 | TSHR (0.58) | EPHX2TSHRCYP4A11CYP4F2ALOX5 | |
| SCHEMBL2851609 | 0.89 | LOXL2 (0.56) | LOXL2EPHX2TSHRCYP4A11CYP4F2 | |
| Hydrochloric Acid SCHEMBL10869249 | 0.88 | TAAR1 (0.47) | EPHX2TSHRCYP4A11CYP4F2ALOX5 | |
| Hydrochloric Acid SCHEMBL926987 | 0.87 | LOXL2 (0.55) | LOXL2EPHX2CYP4A11CYP4F2TPSAB1 | |
| SCHEMBL4841796 | 0.87 | LOXL2 (0.54) | LOXL2TSHRCYP4A11CYP4F2ALDH1A1 | |
| SCHEMBL11139007 | 0.86 | EPHX2 (0.46) | EPHX2TSHRCYP4A11CYP4F2ALOX5 | |
| SCHEMBL1351101 | 0.86 | TSHR (0.48) | EPHX2TSHRCYP4A11CYP4F2ALOX5 | |
| Hydrochloric Acid SCHEMBL4841789 | 0.85 | LOXL2 (0.53) | LOXL2TSHRCYP4A11CYP4F2ALDH1A1 | |
| SCHEMBL11135506 | 0.84 | LOXL2 (0.51) | LOXL2EPHX2CYP4A11CYP4F2TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7465811-B2 | Indoline compounds | LABORATOIRES FOURNIER S.A. (FR) | 2008-12-16 | — | — | US | disclosed |
| US-20080119465-A1 | Novel Indoline Compounds | LABORATORIES FOURNIER S.A. (FR) | 2008-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119465-A1 | Novel Indoline Compounds | GPR119, INSR, IRS1 | LOXL2 4346/4885EPHX2 3674/4885TSHR 681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.