Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4191032 | 0.82 | LTA4H (0.41) | KDM4EGAAMTNR1AMTNR1BLMNA | |
| SCHEMBL9440336 | 0.81 | ALDH1A1 (0.50) | KDM4EGAAMTNR1AMTNR1BLMNA | |
| SCHEMBL11447473 | 0.81 | KDM4E (0.39) | KDM4EGAAMTNR1AMTNR1BLMNA | |
| SCHEMBL4276749 | 0.81 | KDM4E (0.39) | KDM4EGAAMTNR1AMTNR1BLMNA | |
| SCHEMBL2742278 | 0.79 | NPC1 (0.41) | KDM4EGAASIGMAR1 | |
| SCHEMBL10998787 | 0.79 | LTA4H (0.52) | GAALMNAKCNA3SLC6A4MAOA | |
| SCHEMBL10998789 | 0.79 | LTA4H (0.52) | GAALMNAKCNA3SLC6A4MAOA | |
| Ethylene SCHEMBL27857509 | 0.78 | KDM4E (0.37) | KDM4EGAAMTNR1AMTNR1BLMNA | |
| SCHEMBL7611809 | 0.78 | LTA4H (0.34) | GAAMTNR1AMTNR1BKCNA3SLC6A4 | |
| SCHEMBL2127445 | 0.78 | TAAR1 (0.42) | KDM4EGAAKCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008152653-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF TAMSULOSIN HYDROCHLORIDE | MATRIX LABORATORIES LTD (IN) | 2008-12-18 | — | — | WO | disclosed |