SCHEMBL483315

SCHEMBL483315

C=CC(=O)OC(CC)CN

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.39
HPGD P15428 1/20 0.38
ALDH1A1 P00352 5/20 0.33
TP53 P04637 3/20 0.33
HIF1A Q16665 3/20 0.33
CYP3A4 P08684 2/20 0.33
HSD17B10 Q99714 1/20 0.33
THRB P10828 3/20 0.33
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CTSK P43235 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL561301 0.87 TSHR (0.45) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL11501642 0.85 TSHR (0.40) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL23494129 0.82 TSHR (0.47) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL8851039 0.82 TSHR (0.41) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL13950257 0.82 TSHR (0.39) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL3164711 0.82 TSHR (0.41) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL7192136 0.80 TSHR (0.39) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28745668 0.80 TSHR (0.39) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL1132293 0.80 TSHR (0.46) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL11143548 0.80 TSHR (0.39) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4041182-A1 CHARCOAL ADHESIVE COMPOSITION FOR LASHES OR LASH EXTENSIONS Lashify, Inc. (US) 2022-08-17 EP claimed
CN-111356501-A Properties to achieve durable cosmetic Performance 生活实验公司 2020-06-30 CN claimed
US-20090226381-A1 Method and Composition for Reducing the Drying Time of Hair THE PROCTER & GAMBLE COMPANY 2009-09-10 US claimed
WO-2009101546-A1 METHOD AND COMPOSITION FOR REDUCING THE DRYING TIME OF HAIR THE PROCTER & GAMBLE COMPANY (US) 2009-08-20 WO claimed
EP-2090295-A1 Method and composition for reducing the drying time of hair Wella Aktiengesellschaft (DE) 2009-08-19 EP claimed
US-20090098079-A1 PRODUCT RELEASE SYSTEM FOR ATOMIZING COSMETIC HAIR COMPOSITIONS CONTAINING CATIONIC POLYMERS THE PROCTER & GAMBLE COMPANY (US) 2009-04-16 US claimed
EP-1588692-B1 Durable foamed composition WELLA AG (DE) 2008-09-24 EP claimed
US-20080112898-A1 Product release system to atomize polymer-containing cosmetic hair compositions PROCTER & GAMBLE COMPANY, THE 2008-05-15 US claimed
US-20080089855-A1 Non-fluid hair treatment product comprising hair fixative absorbed on waxy carrier THE PROCTER & GAMBLE COMPANY 2008-04-17 US claimed
WO-2008041202-A1 NON-FLUID HAIR TREATMENT PRODUCT COMPRISING HAIR FIXATIVE ABSORBED ON WAXY CARRIER THE PROCTER & GAMBLE COMPANY (US) 2008-04-10 WO claimed
WO-2007002045-A1 PRODUCT RELEASE SYSTEM TO ATOMIZE POLYMER-CONTAINING COSMETIC HAIR COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2007-01-04 WO claimed
WO-2007001842-A1 A PRODUCT RELEASE SYSTEM TO ATOMIZE NON-LIQUID OR HIGHLY VISCOUS COSMETIC COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2007-01-04 WO claimed
EP-1715842-A1 HAIR-TREATMENT AGENT COMPRISING TERPOLYMER FROM VINYL PYRROLIDONE, METHACRYLAMIDE AND VINYL IMIDAZOLE AND ACTIVE INGREDIENTS AND ADDITIVES Wella Aktiengesellschaft (DE) 2006-11-02 EP claimed
EP-1632270-A1 Hair treatment composition containing a polymer combination Wella Aktiengesellschaft (DE) 2006-03-08 EP claimed
EP-1627621-A1 Hair styling gel having a sunscreen effect for the skin and hair Wella Aktiengesellschaft (DE) 2006-02-22 EP claimed
US-20060013785-A1 Hairstyling gels with light protective action for skin and hair WELLA AG (DE) 2006-01-19 US claimed
EP-1588692-A1 Durable foamed composition Wella Aktiengesellschaft (DE) 2005-10-26 EP claimed
US-20050226838-A1 Hair treatment compositions containing N-hydroxy-alkyl-O-benzyl chitosans and methods of using same WELLA AG (DE) 2005-10-13 US claimed
EP-1584323-A1 Use of N-hydroxyalkyl-O-benzylchitosans in hair treatment Wella Aktiengesellschaft (DE) 2005-10-12 EP claimed
WO-2005082322-A1 HAIR-TREATMENT AGENT COMPRISING TERPOLYMER FROM VINYL PYRROLIDONE, METHACRYLAMIDE AND VINYL IMIDAZOLE AND ACTIVE INGREDIENTS AND ADDITIVES WELLA AKTIENGESELLSCHAFT (DE) 2005-09-09 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090098079-A1 PRODUCT RELEASE SYSTEM FOR ATOMIZING COSMETIC HAIR COMPOSITIONS CONTAINING CATIONIC POLYMERS CUTA, POLR1C, MC1R TSHR 1687/4885HPGD 3277/4885ALDH1A1 3537/4885
US-20050226838-A1 Hair treatment compositions containing N-hydroxy-alkyl-O-benzyl chitosans and methods of using same CYP8B1, HAAO, TYR TSHR 4502/4885HPGD 387/4885ALDH1A1 1251/4885
US-20090226381-A1 Method and Composition for Reducing the Drying Time of Hair SUCLG1, POLR1C, SPAST TSHR 3723/4885HPGD 3029/4885ALDH1A1 3937/4885
US-20080112898-A1 Product release system to atomize polymer-containing cosmetic hair compositions CUTA, SUCLG1, POLR1C TSHR 2805/4885HPGD 2876/4885ALDH1A1 3384/4885
US-20060013785-A1 Hairstyling gels with light protective action for skin and hair SUCLG1, CUTA, MTCL3 TSHR 3150/4885HPGD 1467/4885ALDH1A1 853/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.