Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 13/20 | 0.77 |
| ▸ | NPC1 | O15118 | 12/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.77 |
| ▸ | TP53 | P04637 | 4/20 | 0.77 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.57 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.57 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.57 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3195014 | 0.93 | RAB9A (0.77) | RAB9ANPC1SMN1; SMN2TP53ALOX15 | |
| SCHEMBL6799157 | 0.88 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2TP53ALOX15 | |
| SCHEMBL8770881 | 0.83 | RAB9A (0.89) | RAB9ANPC1SMN1; SMN2TP53ALOX15 | |
| SCHEMBL8769709 | 0.83 | RAB9A (0.89) | RAB9ANPC1SMN1; SMN2TP53ALOX15 | |
| SCHEMBL30341896 | 0.83 | RAB9A (0.89) | RAB9ANPC1SMN1; SMN2TP53ALOX15 | |
| SCHEMBL6361263 | 0.83 | RAB9A (0.89) | RAB9ANPC1SMN1; SMN2TP53ALOX15 | |
| SCHEMBL4963650 | 0.83 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2TP53ALOX15 | |
| SCHEMBL22192206 | 0.83 | RAB9A (0.89) | RAB9ANPC1SMN1; SMN2TP53ALOX15 | |
| SCHEMBL2917029 | 0.82 | NPC1 (0.82) | RAB9ANPC1SMN1; SMN2TP53ALOX15 | |
| SCHEMBL4188342 | 0.82 | NPC1 (0.52) | RAB9ANPC1SMN1; SMN2TP53ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 537 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090163515-A1 | Compounds Which Bind to the Active Site of Protein Kinase Enzymes | BIOFOCUS DISCOVERY LTD. | 2009-06-25 | — | — | US | claimed |
| WO-2006072792-A2 | COMPOUNDS WHICH BIND TO THE ACTIVE SITE OF PROTEIN KINASE ENZYMES | GALAPAGOS NV (BE) | 2006-07-13 | — | — | WO | claimed |
| EP-1644365-A2 | PYRAZINE AND PYRIDINE DERIVATIVES AS RHO KINASE INHIBITORS | Biofocus Discovery Ltd (GB) | 2006-04-12 | — | — | EP | claimed |
| WO-2005003101-A2 | PYRAZINE AND PYRIDINE DERIVATIVES AS RHO KINASE INHIBITORS | BIOFOCUS DISCOVERY LIMITED (GB) | 2005-01-13 | — | — | WO | claimed |
| CN-110446739-B | Fluoroacetophenone-containing derivative, fluorine-containing additive, curable composition containing the same, and cured product thereof | DIC株式会社 | 2022-01-11 | — | — | CN | disclosed |
| US-10961405-B2 | Fluorine-containing acetophenone derivative, fluroine based additive, curable composition including same, and cured product thereof | DIC CORPORATION (JP) | 2021-03-30 | — | — | US | disclosed |
| CN-111954849-A | Photosensitive resin composition, cured product, insulating material, resin material for solder resist, and resist member | DIC株式会社 | 2020-11-17 | — | — | CN | disclosed |
| CN-110446739-A | Fluorine-containing acetophenone derivs, fluorine system additive and contain its solidification compound and its solidfied material | DAINIPPON INK & CHEMICALS | 2019-11-12 | — | — | CN | disclosed |
| CN-106414398-B | Compound, active energy ray-curable composition, cured product thereof, printing ink, and ink for inkjet recording | DIC株式会社 | 2019-04-05 | — | — | CN | disclosed |
| EP-1657286-B1 | Radiation curable ink jet ink, comprising a polymerisation initiation sensitising dye | FUJIFILM CORP (JP) | 2018-07-04 | — | — | EP | disclosed |
| US-9957402-B2 | Compound, active energy ray curable composition, cured article thereof, printing ink, and inkjet recording ink | DIC CORPORATION (JP) | 2018-05-01 | — | — | US | disclosed |
| EP-1859954-B2 | Planographic printing plate precursor and stack thereof | FUJIFILM CORP (JP) | 2017-11-08 | — | — | EP | disclosed |
| US-5703140-A | CONTAINS ETHYLENICALLY UNSATURATED BOND, OXIME ETHER COMPOUND, SPECTRAL SENSITIZING DYE | FUJI PHOTO FILM CO., LTD. (JP) | 1997-12-30 | — | — | US | disclosed |
| US-5609992-A | UNSATURATED COMPOUND AND A THIAZOLONE PHOTOSENSITIZER | FUJI PHOTO FILM CO., LTD. (JP) | 1997-03-11 | — | — | US | disclosed |
| EP-0726497-A2 | Photopolymerizable composition | FUJI PHOTO FILM CO., LTD. (JP) | 1996-08-14 | — | — | EP | disclosed |
| EP-0726498-A1 | Photopolymerizable composition | FUJI PHOTO FILM CO., LTD. (JP) | 1996-08-14 | — | — | EP | disclosed |
| EP-0724197-A1 | Photopolymerizable composition | FUJI PHOTO FILM CO., LTD. (JP) | 1996-07-31 | — | — | EP | disclosed |
| EP-0710887-A1 | Photopolymerizable composition | FUJI PHOTO FILM CO., LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |
| US-5053325-A | 2-hydrogen bond donating group-substituted benzoyl acetanilides | KONICA CORPORATION (JP) | 1991-10-01 | — | — | US | disclosed |
| EP-0422505-A1 | Silver halide color photographic light-sensitive material | KONICA CORPORATION (JP) | 1991-04-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163515-A1 | Compounds Which Bind to the Active Site of Protein Kinase Enzymes | ROCK1, ROCK2, CIT | RAB9A 1053/4885NPC1 1679/4885SMN1; SMN2 2400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.