Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIFC1 | Q9BW19 | 5/20 | 0.56 |
| ▸ | FPR2 | P25090 | 1/20 | 0.52 |
| ▸ | CDK2 | P24941 | 1/20 | 0.51 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.50 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.50 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.50 |
| ▸ | MME | P08473 | 3/20 | 0.49 |
| ▸ | ACE | P12821 | 3/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.49 |
| ▸ | CPA1 | P15085 | 2/20 | 0.49 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4833896 | 1.00 | KIFC1 (0.56) | KIFC1FPR2CDK2GPR34ITGB1 | |
| SCHEMBL4824898 | 0.94 | KIFC1 (0.57) | KIFC1FPR2CDK2GPR34ITGB1 | |
| SCHEMBL5926558 | 0.91 | MME (0.57) | ITGB1ITGA4MMEACEACE2 | |
| SCHEMBL27611059 | 0.91 | MME (0.57) | ITGB1ITGA4MMEACEACE2 | |
| SCHEMBL5927352 | 0.89 | KIFC1 (0.61) | KIFC1FPR2CDK2GPR34ITGB1 | |
| SCHEMBL6400298 | 0.89 | KDR (0.56) | KIFC1CDK2ELANE | |
| SCHEMBL6400300 | 0.89 | KDR (0.56) | KIFC1CDK2ELANE | |
| SCHEMBL4831835 | 0.88 | FPR2 (0.56) | KIFC1FPR2GPR34MMEACE | |
| SCHEMBL4831843 | 0.88 | FPR2 (0.56) | KIFC1FPR2GPR34MMEACE | |
| SCHEMBL4831583 | 0.85 | KIFC1 (0.47) | KIFC1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7459472-B2 | Aryl and heteroaryl compounds, compositions, and methods of use | TRANSTECH PHARMA, INC. (US) | 2008-12-02 | — | — | US | disclosed |