Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.37 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17886203 | 0.83 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNANPSR1SMN1; SMN2 | |
| SCHEMBL1523252 | 0.81 | PKM (0.47) | ALDH1A1MAPTLMNANPSR1TP53 | |
| SCHEMBL28018641 | 0.78 | ALDH1A1 (0.45) | ALDH1A1MAPTLMNASMN1; SMN2RAB9A | |
| SCHEMBL335233 | 0.78 | ALDH1A1 (0.45) | ALDH1A1MAPTLMNASMN1; SMN2RAB9A | |
| SCHEMBL1799577 | 0.78 | ALDH1A1 (0.45) | ALDH1A1MAPTLMNATP53SMN1; SMN2 | |
| SCHEMBL1799154 | 0.77 | ALDH1A1 (0.44) | ALDH1A1MAPTLMNANPSR1TP53 | |
| SCHEMBL334730 | 0.77 | ALDH1A1 (0.46) | ALDH1A1MAPTLMNASMN1; SMN2RAB9A | |
| SCHEMBL4779987 | 0.74 | ALDH1A1 (0.39) | ALDH1A1MAPTLMNARAB9AMEN1 | |
| SCHEMBL4063751 | 0.74 | MAPT (0.39) | ALDH1A1MAPTLMNANPSR1SMN1; SMN2 | |
| SCHEMBL7297826 | 0.71 | CYP3A4 (0.52) | ALDH1A1MAPTLMNANPSR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100376572-C | Anti-infective agents | ABBOTT LAB (US) | 2008-03-26 | — | — | CN | disclosed |
| WO-2008011337-A1 | HCV INHIBITORS | ABBOTT LABORATORIES (US) | 2008-01-24 | — | — | WO | disclosed |
| CN-1735612-A | Anti-infective agents | ABBOTT LAB (US) | 2006-02-15 | — | — | CN | disclosed |