Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | S100A4 | P26447 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL335790 | 0.81 | CA12 (0.36) | ALDH1A1MAPTLMNAPOLBMEN1 | |
| SCHEMBL1799577 | 0.79 | ALDH1A1 (0.45) | ALDH1A1MAPTLMNAPOLBMEN1 | |
| SCHEMBL335233 | 0.79 | ALDH1A1 (0.45) | ALDH1A1MAPTLMNAPOLBMEN1 | |
| SCHEMBL17886203 | 0.76 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNAPOLBMEN1 | |
| SCHEMBL4834129 | 0.74 | ALDH1A1 (0.45) | ALDH1A1MAPTLMNAPOLBMEN1 | |
| SCHEMBL335791 | 0.74 | HTR2C (0.38) | ALDH1A1MAPTLMNAPOLBMEN1 | |
| SCHEMBL1523252 | 0.72 | PKM (0.47) | ALDH1A1MAPTLMNAPOLBMEN1 | |
| SCHEMBL28018641 | 0.72 | ALDH1A1 (0.45) | ALDH1A1MAPTLMNAPOLBMEN1 | |
| SCHEMBL1799154 | 0.71 | ALDH1A1 (0.44) | ALDH1A1MAPTLMNAPOLBMEN1 | |
| SCHEMBL332661 | 0.70 | CA2 (0.34) | ALDH1A1MAPTPOLBCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008011337-A1 | HCV INHIBITORS | ABBOTT LABORATORIES (US) | 2008-01-24 | — | — | WO | disclosed |