Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GALR3 | O60755 | 1/20 | 0.40 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30123731 | 0.81 | CYP19A1 (0.46) | CYP19A1ALDH1A1SMN1; SMN2TSHRMAPT | |
| SCHEMBL5327089 | 0.81 | CYP19A1 (0.46) | CYP19A1ALDH1A1SMN1; SMN2TSHRMAPT | |
| SCHEMBL106062 | 0.81 | TSHR (0.50) | CYP19A1ALDH1A1SMN1; SMN2TSHRMAPT | |
| SCHEMBL6958245 | 0.80 | CA1 (0.37) | CYP19A1ALDH1A1SMN1; SMN2TSHRMAPT | |
| SCHEMBL2153612 | 0.80 | CYP19A1 (0.48) | CYP19A1ALDH1A1SMN1; SMN2TSHRMAPT | |
| SCHEMBL2154210 | 0.80 | SMN1; SMN2 (0.49) | CYP19A1ALDH1A1SMN1; SMN2TSHRMAPT | |
| Ethane SCHEMBL2154770 | 0.79 | TSHR (0.48) | CYP19A1ALDH1A1SMN1; SMN2TSHRMAPT | |
| SCHEMBL15018240 | 0.79 | NOTUM (0.36) | CYP19A1ALDH1A1SMN1; SMN2TSHRMAPT | |
| SCHEMBL19356915 | 0.78 | CYP19A1 (0.47) | CYP19A1ALDH1A1SMN1; SMN2TSHRMAPT | |
| SCHEMBL4797057 | 0.77 | CYP19A1 (0.43) | CYP19A1ALDH1A1SMN1; SMN2TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 219 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115572278-B | Genipin derivative and preparation method and application thereof | 北京志道生物科技有限公司 | 2023-09-01 | — | — | CN | claimed |
| US-20230226062-A1 | HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS | INCYTE CORPORATION | 2023-07-20 | — | — | US | claimed |
| CN-115572278-A | Genipin derivative and preparation method and application thereof | 北京志道生物科技有限公司 | 2023-01-06 | — | — | CN | claimed |
| EP-3246328-B1 | QUINAZOLINE HETEROCYCLIC COMPOUND AS EGFR KINASE INHIBITOR, AND PREPARATION AND APPLICATION THEREOF | BEIJING SCITECH MQ PHARMACEUTICALS LTD (CN) | 2020-07-22 | — | — | EP | claimed |
| US-20190053492-A1 | SUBSTITUTED PYRIDINE COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2019-02-21 | — | — | US | claimed |
| EP-3429997-A1 | N-(CYANOBENZYL)-6-(CYCLOPROPYL-CARBONYLAMINO)-4-(PHENYL)-PYRIDINE-2-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS PESTICIDES AND PLANT PROTECTION AGENTS | Bayer CropScience Aktiengesellschaft (DE) | 2019-01-23 | — | — | EP | claimed |
| EP-2978852-B1 | PRODUCTION OF PYRIPYROPENES FROM DRY BIOMASS | BASF SE (DE) | 2018-10-17 | — | — | EP | claimed |
| US-20180177784-A1 | HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS | INCYTE CORPORATION | 2018-06-28 | — | — | US | claimed |
| WO-2018119263-A1 | HETEROCYCLIC COMPOUNDS DERIVATIVES AS PD-L1 INTERNALIZATION INDUCERS | INCYTE CORPORATION (US) | 2018-06-28 | — | — | WO | claimed |
| WO-2017157885-A1 | N-(CYANOBENZYL)-6-(CYCLOPROPYL-CARBONYLAMINO)-4-(PHENYL)-PYRIDINE-2-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS PESTICIDES AND PLANT PROTECTION AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-09-21 | — | — | WO | claimed |
| CN-101505603-A | Boron-containing small molecules | ANACOR PHARMACEUTICALS INC (US) | 2009-08-12 | — | — | CN | claimed |
| EP-1976536-A2 | BORON-CONTAINING SMALL MOLECULES | Anacor Pharmaceuticals, Inc. (US) | 2008-10-08 | — | — | EP | claimed |
| WO-2007078340-A2 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2007-07-12 | — | — | WO | claimed |
| US-20070155699-A1 | Boron-containing small molecules | ANACOR PHARMACEUTICALS (US) | 2007-07-05 | — | — | US | claimed |
| EP-1304325-A1 | 5-(M-CYANOBENZYLAMINO)PYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-04-23 | — | — | EP | claimed |
| EP-0398692-B1 | Alkoxyiminoacetamide derivatives and their use as fungicides | SHIONOGI & CO (JP) | 1996-08-21 | — | — | EP | claimed |
| US-5371222-A | Intermediates | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1994-12-06 | — | — | US | claimed |
| US-5371223-A | Controlling phytopathogens | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1994-12-06 | — | — | US | claimed |
| US-5185342-A | ALKOXYIMINOACETAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1993-02-09 | — | — | US | claimed |
| EP-0398692-A2 | Alkoxyiminoacetamide derivatives and their use as fungicides | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1990-11-22 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190053492-A1 | SUBSTITUTED PYRIDINE COMPOUNDS AS PESTICIDES | CHRM1, CHRM2, ACHE | CYP19A1 249/4885ALDH1A1 606/4885SMN1; SMN2 3186/4885 |
| US-20070155699-A1 | Boron-containing small molecules | ETF1, POLR1C, DPM1 | CYP19A1 2229/4885ALDH1A1 3692/4885SMN1; SMN2 4595/4885 |
| US-20180177784-A1 | HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS | CD274, PDCD1, PDCD1LG2 | CYP19A1 811/4885ALDH1A1 122/4885SMN1; SMN2 4043/4885 |
| US-20230226062-A1 | HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS | CD274, PDCD1, PDCD1LG2 | CYP19A1 811/4885ALDH1A1 122/4885SMN1; SMN2 4043/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.