Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11524213 | 0.83 | GABRA1 (0.41) | CA1CA2SMN1; SMN2HIF1AMAOA | |
| SCHEMBL2096194 | 0.81 | UPP1 (0.31) | HSD11B1 | |
| SCHEMBL483553 | 0.80 | CYP19A1 (0.46) | CA1CA2SMN1; SMN2TSHRMCL1 | |
| SCHEMBL1125092 | 0.79 | SMN1; SMN2 (0.37) | CA1CA2SMN1; SMN2HIF1AMAOA | |
| SCHEMBL28215006 | 0.79 | S1PR1 (0.40) | CA1CA2SMN1; SMN2HIF1AMAOA | |
| SCHEMBL27756124 | 0.79 | SMN1; SMN2 (0.37) | CA1CA2SMN1; SMN2HIF1AMAOA | |
| SCHEMBL23081364 | 0.79 | ALDH1A1 (0.36) | CA1CA2SMN1; SMN2HIF1AMAOA | |
| SCHEMBL8655295 | 0.79 | GABRA1 (0.43) | CA1CA2SMN1; SMN2HIF1AMAOA | |
| SCHEMBL31185609 | 0.79 | GABRA1 (0.43) | CA1CA2SMN1; SMN2HIF1AMAOA | |
| SCHEMBL15018240 | 0.78 | NOTUM (0.36) | CA1CA2SMN1; SMN2TSHRMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |