Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.70 |
| ▸ | CA12 | O43570 | 2/20 | 0.70 |
| ▸ | CA1 | P00915 | 2/20 | 0.70 |
| ▸ | CA2 | P00918 | 2/20 | 0.70 |
| ▸ | CA3 | P07451 | 2/20 | 0.70 |
| ▸ | CA4 | P22748 | 2/20 | 0.70 |
| ▸ | CA6 | P23280 | 2/20 | 0.70 |
| ▸ | CA5A | P35218 | 2/20 | 0.70 |
| ▸ | CA7 | P43166 | 2/20 | 0.70 |
| ▸ | CA9 | Q16790 | 2/20 | 0.70 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.70 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.70 |
| ▸ | PKM | P14618 | 1/20 | 0.70 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.70 |
| ▸ | SNCA | P37840 | 1/20 | 0.70 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.70 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.70 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31380860 | 1.00 | TOP2A (0.78) | TOP2AKDM4ECA12CA1CA2 | |
| SCHEMBL4621488 | 1.00 | TOP2A (0.78) | TOP2AKDM4ECA12CA1CA2 | |
| SCHEMBL10870003 | 0.90 | TOP2A (0.64) | TOP2AKDM4ECA12CA1CA2 | |
| SCHEMBL7252136 | 0.88 | KDM4E (0.73) | TOP2AKDM4ECA12CA1CA2 | |
| SCHEMBL4621755 | 0.88 | KDM4E (0.73) | TOP2AKDM4ECA12CA1CA2 | |
| Ethyl Curcumin SCHEMBL8965258 | 0.88 | TOP2A (1.00) | TOP2AKDM4ECA12CA1CA2 | |
| SCHEMBL4935432 | 0.88 | TOP2A (0.78) | TOP2AKDM4ECA12CA1CA2 | |
| Ethyl Curcumin SCHEMBL8965263 | 0.88 | TOP2A (1.00) | TOP2AKDM4ECA12CA1CA2 | |
| SCHEMBL4935429 | 0.88 | TOP2A (0.78) | TOP2AKDM4ECA12CA1CA2 | |
| SCHEMBL7247313 | 0.88 | KDM4E (0.84) | TOP2AKDM4ECA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0633021-B1 | Chondroprotective agents | KUREHA CHEMICAL IND CO LTD (JP) | 1998-05-06 | — | — | EP | claimed |
| US-5621009-A | ADMINISTERING ALKOXY- AND HYDROXY-SUBSTITUTED CINNAMIC ACIDS FOR TREATMENT AND/OR PREVENTION OF CARTILEGE DISEASES | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1997-04-15 | — | — | US | claimed |
| EP-0633021-A1 | Chondroprotective agents | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1995-01-11 | — | — | EP | claimed |
| EP-0166542-B1 | TRITERPENYL ESTERS OF ORGANIC ACIDS, PROCESS FOR THEIR PRODUCTION, AND HYPOLIPIDEMIC AGENTS COMPOSED OF THEM | AMANO PHARMACEUTICAL CO., LTD. (JP) | 1990-08-08 | — | — | EP | claimed |
| US-4748161-A | Triterpenyl esters of organic acids and hypolipidemic agents composed of them | AMANO PHARMACEUTICAL CO., LTD. (JP) | 1988-05-31 | — | — | US | claimed |
| EP-0166542-A2 | Triterpenyl esters of organic acids, process for their production, and hypolipidemic agents composed of them | AMANO PHARMACEUTICAL CO., LTD. (JP) | 1986-01-02 | — | — | EP | claimed |
| JP-7025759-A | — | — | None | — | — | JP | disclosed |
| JP-1013018-A | — | — | None | — | — | JP | disclosed |
| US-20250129007-A1 | PROCESS FOR PREPARING P-HYDROXYCINNAMIC ACID | SPECIALTY OPERATIONS FRANCE (FR) | 2025-04-24 | — | — | US | disclosed |
| EP-4469428-A1 | PROCESS FOR PREPARING P-HYDROXYCINNAMIC ACID | SPECIALTY OPERATIONS FRANCE (FR) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023144108-A1 | PROCESS FOR PREPARING P-HYDROXYCINNAMIC ACID | RHODIA OPERATIONS (FR) | 2023-08-03 | — | — | WO | disclosed |
| CN-113880695-A | Preparation method of 4-vinylphenol compound | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2022-01-04 | — | — | CN | disclosed |
| CN-108473484-B | Compounds useful as TRPM8 modulators | 弗门尼舍公司 | 2021-06-29 | — | — | CN | disclosed |
| US-5621009-A | ADMINISTERING ALKOXY- AND HYDROXY-SUBSTITUTED CINNAMIC ACIDS FOR TREATMENT AND/OR PREVENTION OF CARTILEGE DISEASES | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1997-04-15 | — | — | US | disclosed |
| JP-H0725759-A | AGENT FOR PROTECTING CARTILAGE | KUREHA CHEM IND CO LTD | 1995-01-27 | — | — | JP | disclosed |
| EP-0633021-A1 | Chondroprotective agents | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1995-01-11 | — | — | EP | disclosed |
| EP-0166542-B1 | TRITERPENYL ESTERS OF ORGANIC ACIDS, PROCESS FOR THEIR PRODUCTION, AND HYPOLIPIDEMIC AGENTS COMPOSED OF THEM | AMANO PHARMACEUTICAL CO., LTD. (JP) | 1990-08-08 | — | — | EP | disclosed |
| JP-S6413018-A | SKIN-BEAUTIFYING COSMETIC | POLA CHEM IND INC | 1989-01-17 | — | — | JP | disclosed |
| US-4748161-A | Triterpenyl esters of organic acids and hypolipidemic agents composed of them | AMANO PHARMACEUTICAL CO., LTD. (JP) | 1988-05-31 | — | — | US | disclosed |
| EP-0166542-A2 | Triterpenyl esters of organic acids, process for their production, and hypolipidemic agents composed of them | AMANO PHARMACEUTICAL CO., LTD. (JP) | 1986-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250129007-A1 | PROCESS FOR PREPARING P-HYDROXYCINNAMIC ACID | HPD, HAAO, PAH | TOP2A 2936/4885KDM4E 3192/4885CA12 1222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.