⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15153753 | 0.84 | — | — | |
| SCHEMBL6710755 | 0.78 | — | — | |
| SCHEMBL5685984 | 0.73 | — | — | |
| SCHEMBL9412802 | 0.70 | ALDH1A1 (0.31) | — | |
| SCHEMBL4625493 | 0.67 | — | — | |
| SCHEMBL1360804 | 0.64 | ALDH1A1 (0.40) | — | |
| SCHEMBL15153774 | 0.64 | — | — | |
| SCHEMBL30415589 | 0.64 | ALDH1A1 (0.40) | — | |
| SCHEMBL8070252 | 0.64 | — | — | |
| SCHEMBL7337297 | 0.63 | S1PR4 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12509583-B2 | Particle surface modification to increase compatibility and stability in hydrogels | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2025-12-30 | — | — | US | disclosed |
| EP-1405624-B1 | SURFACE-TREATED POWDER AND COSMETIC PREPARATION | SHINETSU CHEMICAL CO (JP) | 2012-02-01 | — | — | EP | disclosed |
| US-7722899-B2 | Surface-treated powder and cosmetic preparation | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2010-05-25 | — | — | US | disclosed |
| US-20090247662-A1 | Contact Lens Material | MATSUMOTO MASAHIRO | 2009-10-01 | — | — | US | disclosed |
| US-20070149699-A1 | Contact lens material | MENICON CO., LTD. (JP) | 2007-06-28 | — | — | US | disclosed |
| US-7044598-B2 | Lens for eye and method for marking thereof | MENICON CO., LTD.. (JP) | 2006-05-16 | — | — | US | disclosed |
| US-20050206843-A1 | Lens for eye and method for marking thereof | MENICON CO., LTD. (JP) | 2005-09-22 | — | — | US | disclosed |
| EP-1566684-A1 | LENS FOR EYE AND METHOD FOR MARKING THEREOF | MENICON CO., LTD. (JP) | 2005-08-24 | — | — | EP | disclosed |
| EP-0862068-B1 | Plastic articles for medical use | JOHNSON & JOHNSON VISION CARE (US) | 2005-06-01 | — | — | EP | disclosed |
| US-20040156809-A1 | Acrylic/silicone copolymer having at least one hydrolyzable silyl group; waterproof, sebum resistance, storage stability | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
| EP-1405624-A1 | SURFACE-TREATED POWDER AND COSMETIC PREPARATION | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2004-04-07 | — | — | EP | disclosed |
| US-6638991-B2 | Lens material comprising a copolymer derived from a polysiloxane endcapped with acrylated urethane groups, a silicon-containing alkyl methacrylate, a hydrophilic monomer, and a crosslinking monomer; oxygen permeability, strength | MENICON CO., LTD. (JP) | 2003-10-28 | — | — | US | disclosed |
| US-20030197833-A1 | Process for producing an ocular lens having a highly hydrophilic lens surface and ocular lens produced by the process | MENICON CO., LTD. (JP) | 2003-10-23 | — | — | US | disclosed |
| EP-1352735-A2 | Process for producing an ocular lens having a highly hydrophilic lens surface and ocular lens produced by the process | Menicon Co., Ltd. (JP) | 2003-10-15 | — | — | EP | disclosed |
| US-20020198280-A1 | Material for ocular lens | MENICON CO., LTD. (JP) | 2002-12-26 | — | — | US | disclosed |
| EP-1033590-A2 | Ocular lens material | Menicon Co., Ltd. (JP) | 2000-09-06 | — | — | EP | disclosed |
| EP-0862068-A2 | Plastic articles for medical use | TORAY INDUSTRIES, INC. (JP) | 1998-09-02 | — | — | EP | disclosed |
| EP-0600269-A2 | Soft ocular lens material | Menicon Co., Ltd. (JP) | 1994-06-08 | — | — | EP | disclosed |
| US-5206298-A | GRAFT COPOLYMER, SOLUTION CONTAINING THE GRAFT COPOLYMER FOR TREATING CONTACT LENS, AND METHOD OF TREATING CONTACT LENS WITH THE SOLUTION AND MAKING HYDROPHILIC LENS SURFACE | TOMEI SANGYO KABUSHIKI KAISHA (JP) | 1993-04-27 | — | — | US | disclosed |