Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | F7 | P08709 | 1/20 | 0.33 |
| ▸ | F3 | P13726 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6729763 | 0.79 | TRPV4 (0.46) | TSHRHSD17B10MAPK1CASP1TDP1 | |
| SCHEMBL3681025 | 0.74 | KMT2A (0.47) | TSHRMAPK1TDP1KMT2AALDH1A1 | |
| SCHEMBL27346994 | 0.73 | GABRA1 (0.37) | KMT2AALDH1A1MEN1MAPTGAA | |
| SCHEMBL1360804 | 0.73 | ALDH1A1 (0.40) | TSHRHSD17B10MAPK1KMT2AALDH1A1 | |
| SCHEMBL30415589 | 0.73 | ALDH1A1 (0.40) | TSHRHSD17B10MAPK1KMT2AALDH1A1 | |
| SCHEMBL8832653 | 0.71 | LMNA (0.47) | S1PR4TSHRMAPK1TDP1KMT2A | |
| SCHEMBL5685984 | 0.70 | — | — | |
| SCHEMBL28422184 | 0.69 | TDP1 (0.44) | TSHRHSD17B10F7F3DYRK1A | |
| SCHEMBL589945 | 0.69 | CYP3A4 (0.41) | HSD17B10F7F3DYRK1AMAPK1 | |
| SCHEMBL31615190 | 0.69 | CYP3A4 (0.41) | HSD17B10F7F3DYRK1AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5430047-A | Neurotensin antagonists | WARNER-LAMBERT COMPANY (US) | 1995-07-04 | — | — | US | disclosed |