Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 4/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.51 |
| ▸ | PI4KA | P42356 | 2/20 | 0.51 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.51 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.51 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.51 |
| ▸ | DPP4 | P27487 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.51 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.51 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.51 |
| ▸ | GAPDH | P04406 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.51 |
| ▸ | STAT6 | P42226 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.51 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13986326 | 1.00 | ADORA1 (0.51) | ADORA1ADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL13986329 | 1.00 | ADORA1 (0.51) | ADORA1ADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL13773257 | 0.91 | ADORA3 (0.61) | ADORA1ADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL22220276 | 0.91 | ADORA3 (0.61) | ADORA1ADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL21859283 | 0.91 | ADORA3 (0.61) | ADORA1ADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL21859152 | 0.91 | ADORA3 (0.61) | ADORA1ADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL22220139 | 0.91 | ADORA3 (0.61) | ADORA1ADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL30446694 | 0.91 | ADORA3 (0.61) | ADORA1ADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL21859151 | 0.90 | ADORA1 (0.50) | ADORA1ADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL6762689 | 0.90 | ADORA1 (0.50) | ADORA1ADORA3PI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111434671-A | Liver specificity AMPK agonist and preparation method and application thereof | 凯思凯迪（上海）医药科技有限公司 | 2020-07-21 | — | — | CN | disclosed |
| WO-2020143800-A1 | LIVER-SPECIFIC AMPK AGONIST, PREPARATION METHOD THEREFOR AND USES THEREOF | 凯思凯迪（上海）医药科技有限公司 | 2020-07-16 | — | — | WO | disclosed |
| US-7465544-B2 | Synthetic cofactor analogs of S-adenosylmethionine as ligatable probes of biological methylation and methods for their use | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-12-16 | — | — | US | disclosed |
| US-20070161007-A1 | Synthetic cofactor analogs of S-adenosylmethionine as ligatable probes of biological methylation and methods for their use | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2007-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070161007-A1 | Synthetic cofactor analogs of S-adenosylmethionine as ligatable probes of biological methylation and methods for their use | DNMT1, MAT2A, MAT1A | ADORA1 294/4885ADORA3 236/4885PI4KA 2765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.