Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionaldehyde SCHEMBL1523503 | 0.84 | LMNA (0.67) | LMNATHRBALDH1A1MAPK1TDP1 | |
| SCHEMBL909547 | 0.84 | LMNA (0.52) | LMNATHRBALDH1A1 | |
| Malonaldehyde SCHEMBL6704192 | 0.82 | LMNA (0.63) | LMNATHRBALDH1A1MAPK1TDP1 | |
| SCHEMBL11485155 | 0.82 | LMNA (0.63) | LMNATHRBALDH1A1MAPK1TDP1 | |
| SCHEMBL4293299 | 0.81 | LMNA (0.71) | LMNATHRBALDH1A1MAPK1TDP1 | |
| Acetaldehyde SCHEMBL212729 | 0.81 | LMNA (0.71) | LMNATHRBALDH1A1MAPK1TDP1 | |
| Methylene Chloride SCHEMBL7997683 | 0.81 | LMNA (0.80) | LMNATHRBALDH1A1MAPK1 | |
| SCHEMBL9077586 | 0.81 | LMNA (0.48) | LMNAALDH1A1 | |
| Ethylene SCHEMBL11409706 | 0.81 | LMNA (0.48) | LMNAALDH1A1 | |
| SCHEMBL9192876 | 0.80 | LMNA (0.60) | LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113234076-B | Preparation method of doxofylline | 湖北午时药业股份有限公司 | 2023-08-18 | — | — | CN | claimed |
| CN-116554121-A | Synthesis method of 2-isobutyl thiazole | 济南悟通生物科技有限公司 | 2023-08-08 | — | — | CN | claimed |
| CN-114853692-B | Preparation method of 2-aminothiazole | 广东省科学院化工研究所 | 2023-05-23 | — | — | CN | claimed |
| CN-115466176-A | Method for preparing chloroacetaldehyde, chloroacetaldehyde acetal, 2, 5-dihydroxy-1, 4-dithiane and 2-aminothiazole in anhydrous phase | 江西帝劢药业有限公司 | 2022-12-13 | — | — | CN | claimed |
| CN-114853692-A | Preparation method of 2-aminothiazole | 广东省科学院化工研究所 | 2022-08-05 | — | — | CN | claimed |
| CN-105985313-B | The method for being used to prepare chloroacetaldehyde acetal | 瓦克化学股份公司 | 2019-07-09 | — | — | CN | claimed |
| EP-3070082-B1 | PROCESS FOR PREPARING CHLOROACETALDEHYDE ACETALS | WACKER CHEMIE AG (DE) | 2018-05-09 | — | — | EP | claimed |
| US-9896428-B2 | Process for preparing chloroacetaldehyde acetals | WACKER CHEMIE AG (DE) | 2018-02-20 | — | — | US | claimed |
| US-20160272610-A1 | PROCESS FOR PREPARING CHLOROACETALDEHYDE ACETALS | WACKER CHEMIE AG (DE) | 2016-09-22 | — | — | US | claimed |
| US-6844375-B2 | 4-methylene-1,3-dioxolanes as cross-linking agents | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-01-18 | — | — | US | claimed |
| US-5576465-A | DEHYDROETHERIFICATION OF ACETALS OR KETALS BY HEATING | HUELS AKTIENGESELLSCHAFT (DE) | 1996-11-19 | — | — | US | claimed |
| EP-0202157-B1 | N-SUBSTITUTED 2-AMINO-THIAZOLES, PROCESS FOR THEIR PREPARATION AND THEIR THERAPEUTICAL USE | LABORATOIRES CHAUVIN S.A. (FR) | 1989-08-23 | — | — | EP | claimed |
| EP-0247234-A1 | Process for the manufacture of acetals of chloro- or bromoacetaldehyde | National Starch and Chemical Corporation (US) | 1987-12-02 | — | — | EP | claimed |
| US-4642390-A | Process for the manufacture of acetals of chloroacetaldehyde | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1987-02-10 | — | — | US | claimed |
| EP-0202157-A1 | N-substituted 2-amino-thiazoles, process for their preparation and their therapeutical use | LABORATOIRES CHAUVIN S.A. (FR) | 1986-11-20 | — | — | EP | claimed |
| CN-116063163-B | Preparation method of 7- (benzyloxy) -2,4,5, 6-tetrahydro-1H-cyclobutadiene [ f ] indene-1-one | 上海毕臣生化科技有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-113234076-B | Preparation method of doxofylline | 湖北午时药业股份有限公司 | 2023-08-18 | — | — | CN | disclosed |
| US-4115578-A | FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1978-09-19 | — | — | US | disclosed |
| US-4105762-A | Metal salt complexes of 1-substituted aralkyl imidazoles, and methods and compositions for controlling phytopathogenic fungi using them | ROHM AND HAAS COMPANY (US) | 1978-08-08 | — | — | US | disclosed |
| US-3947451-A | TREATMENT OF PSYCHIATRIC AND PSYCHOSOMATIC DISEASES | AB KABI (SW) | 1976-03-30 | — | — | US | disclosed |