Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.38 |
| ▸ | GAA | P10253 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 5/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.34 |
| ▸ | CASP1 | P29466 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL221413 | 0.78 | ALDH1A1 (0.35) | CA1CA2ALDH1A1KDM4EGAA | |
| SCHEMBL9859801 | 0.70 | ALDH1A1 (0.40) | CA1CA2ALDH1A1GAAMAPT | |
| SCHEMBL28217149 | 0.70 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2ACYP2A6HSD17B10 | |
| SCHEMBL22684751 | 0.70 | CA1 (0.41) | CA1CA2MEN1KMT2ATSHR | |
| SCHEMBL11031530 | 0.69 | KDM4E (0.35) | CA1CA2ALDH1A1KDM4EGAA | |
| SCHEMBL31429764 | 0.69 | KDM4E (0.42) | CA1CA2ALDH1A1KDM4EGAA | |
| SCHEMBL4079696 | 0.65 | CYP2A6 (0.42) | ALDH1A1MAPTCYP2A6HSD17B10TSHR | |
| SCHEMBL21179481 | 0.65 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2ACYP2A6HSD17B10 | |
| SCHEMBL4897405 | 0.65 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2ACYP2A6HSD17B10 | |
| SCHEMBL1097671 | 0.65 | CYP2A6 (0.42) | ALDH1A1KDM4EGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3620455-A1 | NEW PREPARATION METHOD FOR ESCITALOPRAM PAMOATE | Zhejiang Huahai Pharmaceutical Co., Ltd (CN) | 2020-03-11 | — | — | EP | disclosed |
| CN-108976188-A | A kind of preparation method that escitalopram embonate is new | 上海奥博生物医药技术有限公司 | 2018-12-11 | — | — | CN | disclosed |
| CN-108976188-A | A kind of preparation method that escitalopram embonate is new | 上海奥博生物医药技术有限公司 | 2018-12-11 | — | — | CN | disclosed |
| US-7411077-B2 | Process for the preparation of a cyano-isobenzofuran | ADORKEN TECHNOLOGY SPA (IT) | 2008-08-12 | — | — | US | disclosed |
| US-7411077-B2 | Process for the preparation of a cyano-isobenzofuran | ADORKEN TECHNOLOGY SPA (IT) | 2008-08-12 | — | — | US | disclosed |
| US-20060293297-A1 | Cyanofluoropyrrolidine derviative | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2006-12-28 | — | — | US | disclosed |
| US-20060183925-A1 | Process for the preparation of a cyano-isobenzofuran | ADORKEM TECHNOLOGY SPA | 2006-08-17 | — | — | US | disclosed |
| US-20060183925-A1 | Process for the preparation of a cyano-isobenzofuran | ADORKEM TECHNOLOGY SPA | 2006-08-17 | — | — | US | disclosed |
| CN-1761658-A | Process for the preparation of a cyano-isobenzofuran | ADORKEM TECHNOLOGY SPA (IT) | 2006-04-19 | — | — | CN | disclosed |
| CN-1761658-A | Process for the preparation of a cyano-isobenzofuran | ADORKEM TECHNOLOGY SPA (IT) | 2006-04-19 | — | — | CN | disclosed |
| EP-1627870-A1 | CYANOFLUOROPYRROLIDINE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2006-02-22 | — | — | EP | disclosed |
| EP-1601662-A1 | PROCESS FOR THE PREPARATION OF A CYANO-ISOBENZOFURAN | Adorkem Technology SpA (IT) | 2005-12-07 | — | — | EP | disclosed |
| WO-2004080988-A1 | PROCESS FOR THE PREPARATION OF A CYANO-ISOBENZOFURAN | ADORKEM TECHNOLOGY SPA (IT) | 2004-09-23 | — | — | WO | disclosed |
| CN-1129593-C | Method for prepn. of citalopram | LUNDBECK & CO AS H (DK) | 2003-12-03 | — | — | CN | disclosed |
| CN-1356993-A | Method for prepn. of citalopram | LUNDBECK & CO AS H (DK) | 2002-07-03 | — | — | CN | disclosed |
| US-4090027-A | APPETITE SUPPRESSANTS | HOFFMANN-LA ROCHE INC. (US) | 1978-05-16 | — | — | US | disclosed |
| US-4077978-A | APPETITE SUPPRESSANTS | HOFFMANN-LA ROCHE INC. (US) | 1978-03-07 | — | — | US | disclosed |
| US-3996374-A | Isoindole derivatives as appetite suppressants | HOFFMANN-LA ROCHE INC. (US) | 1976-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060293297-A1 | Cyanofluoropyrrolidine derviative | DPP4, DPP3, NPY4R | CA1 1148/4885CA2 274/4885ALDH1A1 3197/4885 |
| US-20060183925-A1 | Process for the preparation of a cyano-isobenzofuran | HTR1F, CYP4F12, CYP4F3 | CA1 958/4885CA2 1032/4885ALDH1A1 574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.