Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27517494 | 0.75 | CA1 (0.55) | ALDH1A1SMN1; SMN2MAPTCA1CA2 | |
| SCHEMBL2153612 | 0.73 | CYP19A1 (0.48) | ALDH1A1SMN1; SMN2MAPTCA1CA2 | |
| SCHEMBL11031530 | 0.73 | KDM4E (0.35) | ALDH1A1MAPTCA1CA2HTT | |
| SCHEMBL9859945 | 0.72 | SMN1; SMN2 (0.40) | ALDH1A1SMN1; SMN2MAPTCA1CA2 | |
| SCHEMBL4837030 | 0.70 | CA1 (0.47) | ALDH1A1MAPTCA1CA2HTT | |
| SCHEMBL4068907 | 0.68 | CA1 (0.55) | ALDH1A1SMN1; SMN2MAPTCA1CA2 | |
| SCHEMBL1746782 | 0.66 | MAOB (0.40) | ALDH1A1MAPTGAATSHRHSD17B10 | |
| SCHEMBL1252940 | 0.66 | TSHR (0.48) | ALDH1A1SMN1; SMN2MAPTCYP19A1TSHR | |
| SCHEMBL9739681 | 0.66 | HTR2A (0.43) | ALDH1A1MAPTGAATSHRHSD17B10 | |
| SCHEMBL9935525 | 0.66 | TDP1 (0.35) | ALDH1A1GAATSHRHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1052672-A | Benzofuran derivative | GLAXO GROUP LTD (GB) | 1991-07-03 | — | — | CN | disclosed |
| EP-0434249-A2 | Benzofuran derivatives | GLAXO GROUP LIMITED (GB) | 1991-06-26 | — | — | EP | disclosed |