Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT3A | Q9Y6K1 | 2/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.44 |
| ▸ | EHMT2 | Q96KQ7 | 5/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | CCR3 | P51677 | 1/20 | 0.42 |
| ▸ | SSTR5 | P35346 | 3/20 | 0.42 |
| ▸ | NSD2 | O96028 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4834586 | 0.90 | ACHE (0.48) | DNMT3AMCHR1EHMT2HRH1CCR3 | |
| SCHEMBL5193262 | 0.84 | EHMT2 (0.54) | DNMT3AMCHR1EHMT2NSD2MEN1 | |
| Hydrochloric Acid SCHEMBL4839148 | 0.83 | EHMT2 (0.53) | DNMT3AMCHR1EHMT2NSD2MEN1 | |
| SCHEMBL5195218 | 0.82 | MCHR1 (0.64) | MCHR1 | |
| Hydrochloric Acid SCHEMBL4843807 | 0.81 | MCHR1 (0.63) | MCHR1 | |
| SCHEMBL5195313 | 0.81 | MCHR1 (0.45) | DNMT3AMCHR1EHMT2HRH1SSTR5 | |
| Hydrochloric Acid SCHEMBL4839475 | 0.80 | MCHR1 (0.44) | DNMT3AMCHR1EHMT2HRH1SSTR5 | |
| SCHEMBL4843124 | 0.79 | EHMT2 (0.54) | DNMT3AMCHR1EHMT2NSD2MEN1 | |
| SCHEMBL5193639 | 0.78 | EHMT2 (0.54) | DNMT3AMCHR1EHMT2NSD2MEN1 | |
| SCHEMBL4841940 | 0.77 | ACHE (0.49) | DNMT3AMCHR1EHMT2NSD2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7423030-B2 | 1-amino-phthalazine derivatives, the preparation and the therapeutic use thereof | SANOFI-AVENTIS (FR) | 2008-09-09 | — | — | US | claimed |
| EP-1737840-B1 | 1-AMINO-PHTHALAZINE DERIVATIVES, THE PREPARATION AND THE THERAPEUTIC USE THEREOF | SANOFI AVENTIS (FR) | 2007-09-12 | — | — | EP | claimed |
| US-20070099895-A1 | 1-AMINO-PHTHALAZINE DERIVATIVES, THE PREPARATION AND THE THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2007-05-03 | — | — | US | claimed |
| US-7423030-B2 | 1-amino-phthalazine derivatives, the preparation and the therapeutic use thereof | SANOFI-AVENTIS (FR) | 2008-09-09 | — | — | US | disclosed |
| EP-1737840-B1 | 1-AMINO-PHTHALAZINE DERIVATIVES, THE PREPARATION AND THE THERAPEUTIC USE THEREOF | SANOFI AVENTIS (FR) | 2007-09-12 | — | — | EP | disclosed |
| US-20070099895-A1 | 1-AMINO-PHTHALAZINE DERIVATIVES, THE PREPARATION AND THE THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099895-A1 | 1-AMINO-PHTHALAZINE DERIVATIVES, THE PREPARATION AND THE THERAPEUTIC USE THEREOF | CYP11B2, CYP11B1, GOT2 | DNMT3A 4219/4885MCHR1 1335/4885EHMT2 1339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.