Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
| ▸ | TIPARP | Q7Z3E1 | 4/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | TBK1 | Q9UHD2 | 3/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4844672 | 0.93 | DRD2 (0.45) | DRD2DRD3TBK1ACHE | |
| Trifluoroacetic Acid SCHEMBL4842199 | 0.89 | KMT2A (0.44) | DGAT1KCNH2PARP1PARP2TIPARP | |
| Trifluoroacetic Acid SCHEMBL4840505 | 0.87 | DRD2 (0.55) | DRD2DRD3ACHE | |
| Trifluoroacetic Acid SCHEMBL4839705 | 0.87 | DRD2 (0.43) | DRD2DRD3CHEK2TBK1KCNA5 | |
| Trifluoroacetic Acid SCHEMBL4844003 | 0.86 | HRH3 (0.47) | DRD2DRD3CHEK2TBK1ACHE | |
| Trifluoroacetic Acid SCHEMBL4842301 | 0.86 | DRD2 (0.54) | DRD2DRD3CHEK2TBK1ACHE | |
| Trifluoroacetic Acid SCHEMBL4843197 | 0.85 | TBK1 (0.51) | DRD3CHEK2TBK1ACHE | |
| Trifluoroacetic Acid SCHEMBL4841456 | 0.85 | CHEK2 (0.45) | DRD2DRD3CHEK2TBK1ACHE | |
| Trifluoroacetic Acid SCHEMBL4842116 | 0.85 | CHEK2 (0.53) | PARP1CHEK2TBK1ACHE | |
| SCHEMBL6245898 | 0.85 | CHEK2 (0.41) | DGAT1KCNH2PARP1TIPARPDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7410966-B2 | Use of and some novel imidazopyridines | ASTRAZENECA AB (SE) | 2008-08-12 | — | — | US | disclosed |
| US-20050261333-A1 | Use of and some novel imidazopyridines | ASTRAZENECA A B (SE) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261333-A1 | Use of and some novel imidazopyridines | ITK, CSNK1A1, RPS6KA1 | DGAT1 4827/4885KCNH2 497/4885PARP1 2096/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.