Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 2/20 | 0.45 |
| ▸ | TBK1 | Q9UHD2 | 5/20 | 0.44 |
| ▸ | ACHE | P22303 | 8/20 | 0.43 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.41 |
| ▸ | ULK1 | O75385 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4843197 | 0.93 | TBK1 (0.51) | CHEK2TBK1ACHEIKBKEULK1 | |
| Trifluoroacetic Acid SCHEMBL4842116 | 0.93 | CHEK2 (0.53) | CHEK2TBK1ACHEIKBKEADORA3 | |
| Trifluoroacetic Acid SCHEMBL4840800 | 0.92 | CHEK2 (0.45) | CHEK2TBK1ACHEIKBKEULK1 | |
| SCHEMBL4843624 | 0.92 | ACHE (0.50) | CHEK2TBK1ACHEIKBKEPDK1 | |
| Trifluoroacetic Acid SCHEMBL4834798 | 0.91 | CYP4F2 (0.49) | CHEK2TBK1ACHEIKBKEDRD3 | |
| Trifluoroacetic Acid SCHEMBL4841636 | 0.91 | ACHE (0.53) | CHEK2TBK1ACHEIKBKEULK1 | |
| Trifluoroacetic Acid SCHEMBL5258099 | 0.90 | TBK1 (0.44) | CHEK2TBK1ACHEIKBKE | |
| Trifluoroacetic Acid SCHEMBL4842301 | 0.90 | DRD2 (0.54) | CHEK2TBK1ACHEDRD2DRD3 | |
| Trifluoroacetic Acid SCHEMBL4846269 | 0.90 | CHEK2 (0.44) | CHEK2TBK1ACHEIKBKE | |
| Trifluoroacetic Acid SCHEMBL4844160 | 0.89 | ALDH1A1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7410966-B2 | Use of and some novel imidazopyridines | ASTRAZENECA AB (SE) | 2008-08-12 | — | — | US | disclosed |
| EP-1539759-B1 | NOVEL IMIDAZOPYRIDINES AND THEIR USE | ASTRAZENECA AB (SE) | 2007-08-15 | — | — | EP | disclosed |
| US-20050261333-A1 | Use of and some novel imidazopyridines | ASTRAZENECA A B (SE) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261333-A1 | Use of and some novel imidazopyridines | ITK, CSNK1A1, RPS6KA1 | CHEK2 309/4885TBK1 1029/4885ACHE 1390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.