SCHEMBL4838281

SCHEMBL4838281

NCCCc1ccc(CC(=O)O)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.66
ALDH1A1 P00352 2/20 0.66
HPGD P15428 2/20 0.66
CA2 P00918 1/20 0.54
CAMK2A Q9UQM7 1/20 0.54
AKR1B1 P15121 1/20 0.52
LMNA P02545 2/20 0.50
GAA P10253 2/20 0.50
TSHR P16473 2/20 0.50
ABCC4 O15439 1/20 0.50
PTGS1 P23219 1/20 0.50
HTT P42858 1/20 0.50
MAOA P21397 1/20 0.48
HTR2A P28223 1/20 0.47
ANPEP P15144 1/20 0.46
ENPEP Q07075 1/20 0.46
FFAR1 O14842 1/20 0.46
HDAC3 O15379 1/20 0.45
MAPK1 P28482 1/20 0.45
ADRA1A P35348 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11104531 0.98 ALDH1A1 (0.63) HSD17B10ALDH1A1HPGDCA2CAMK2A
SCHEMBL2291602 0.94 ALDH1A1 (0.67) HSD17B10ALDH1A1HPGDCA2CAMK2A
SCHEMBL11137338 0.92 ALDH1A1 (0.65) HSD17B10ALDH1A1HPGDCA2CAMK2A
SCHEMBL4842994 0.87 ALDH1A1 (0.59) HSD17B10ALDH1A1HPGDCA2CAMK2A
SCHEMBL11423252 0.87 ALDH1A1 (0.80) HSD17B10ALDH1A1HPGDCA2CAMK2A
SCHEMBL7820960 0.87 HSD17B10 (0.76) HSD17B10ALDH1A1HPGDCA2CAMK2A
Hydrochloric Acid SCHEMBL11112435 0.85 ALDH1A1 (0.57) HSD17B10ALDH1A1HPGDCA2CAMK2A
SCHEMBL11432001 0.85 ALDH1A1 (0.77) HSD17B10ALDH1A1HPGDCA2CAMK2A
SCHEMBL11424079 0.85 ALDH1A1 (0.77) HSD17B10ALDH1A1HPGDCA2CAMK2A
SCHEMBL11426403 0.85 ALDH1A1 (0.77) HSD17B10ALDH1A1HPGDCA2CAMK2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7465811-B2 Indoline compounds LABORATOIRES FOURNIER S.A. (FR) 2008-12-16 US disclosed
US-20080119465-A1 Novel Indoline Compounds LABORATORIES FOURNIER S.A. (FR) 2008-05-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080119465-A1 Novel Indoline Compounds GPR119, INSR, IRS1 HSD17B10 691/4885ALDH1A1 1819/4885HPGD 3316/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.