Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.30 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HRH2 | P25021 | 1/20 | 0.30 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4790983 | 0.84 | ALDH1A1 (0.34) | ALDH1A1TDP1LMNAADCY5ADORA2A | |
| SCHEMBL4793952 | 0.84 | ALDH1A1 (0.38) | ALDH1A1TDP1LMNAADCY5ADORA2A | |
| SCHEMBL4793888 | 0.83 | ALDH1A1 (0.33) | ALDH1A1TDP1LMNAADORA2APOLB | |
| SCHEMBL4791709 | 0.82 | ALDH1A1 (0.36) | ALDH1A1TDP1LMNAADCY5ADORA2A | |
| SCHEMBL4792640 | 0.80 | TLR7 (0.33) | ALDH1A1TDP1LMNAADORA2APOLB | |
| SCHEMBL4793899 | 0.80 | ALDH1A1 (0.43) | ALDH1A1TDP1KDM4EHPGDADORA2A | |
| SCHEMBL4792244 | 0.79 | MAPK13 (0.38) | ALDH1A1TDP1KDM4ELMNATSHR | |
| SCHEMBL6778610 | 0.79 | ALDH1A1 (0.38) | ALDH1A1TDP1ADORA2ATMIGD3ADORA1 | |
| SCHEMBL4876618 | 0.79 | YTHDC1 (0.38) | POLBKCNH2 | |
| SCHEMBL4794192 | 0.79 | MAPK13 (0.37) | ALDH1A1TDP1LMNAADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513524-A4 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M INNOVATIVE PROPERTIES CO (US) | 2008-09-03 | — | — | EP | disclosed |
| EP-1513524-A2 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M Innovative Properties Company (US) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003103584-A2 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-12-18 | — | — | WO | disclosed |