Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | BRAF | P15056 | 8/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PDE8A | O60658 | 1/20 | 0.32 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4877536 | 0.97 | YTHDC1 (0.39) | YTHDC1POLBL3MBTL1BRAFKCNH2 | |
| SCHEMBL5340121 | 0.84 | HSP90B1 (0.37) | YTHDC1POLBL3MBTL1HTTSLC40A1 | |
| SCHEMBL4791328 | 0.83 | HSP90B1 (0.36) | YTHDC1POLBL3MBTL1HTTSLC40A1 | |
| SCHEMBL4794291 | 0.81 | HSP90B1 (0.37) | YTHDC1POLBL3MBTL1HTTSLC40A1 | |
| SCHEMBL4865127 | 0.81 | MGAT2 (0.39) | BRAFKCNH2 | |
| SCHEMBL4873557 | 0.80 | TLR7 (0.43) | — | |
| SCHEMBL4870522 | 0.79 | TLR7 (0.42) | — | |
| SCHEMBL4876728 | 0.79 | TLR7 (0.40) | L3MBTL1BRAFPIK3CDPIK3CAPIK3CB | |
| SCHEMBL4838352 | 0.79 | ALDH1A1 (0.33) | POLBKCNH2 | |
| SCHEMBL4791912 | 0.79 | TLR7 (0.35) | KCNH2HSP90B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513524-A4 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M INNOVATIVE PROPERTIES CO (US) | 2008-09-03 | — | — | EP | disclosed |
| EP-1513524-A2 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M Innovative Properties Company (US) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003103584-A2 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-12-18 | — | — | WO | disclosed |