Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA3 | P07451 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CA6 | P23280 | 2/20 | 0.33 |
| ▸ | CA5A | P35218 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ODC1 | P11926 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL2162746 | 1.00 | NFKB1 (0.36) | NFKB1TSHRALDH1A1CA12CA1 | |
| Ethylenediamine SCHEMBL4073876 | 1.00 | — | — | |
| Ethylenediamine SCHEMBL10703973 | 0.94 | NFKB1 (0.33) | NFKB1TSHRALDH1A1CA12CA1 | |
| Ethylenediamine SCHEMBL19066603 | 0.94 | NFKB1 (0.33) | NFKB1TSHRALDH1A1CA12CA1 | |
| Ethylenediamine SCHEMBL371424 | 0.94 | NFKB1 (0.33) | NFKB1TSHRALDH1A1CA12CA1 | |
| Ethylenediamine SCHEMBL1444622 | 0.94 | NFKB1 (0.33) | NFKB1TSHRALDH1A1CA12CA1 | |
| Ethylenediamine SCHEMBL8667785 | 0.94 | NFKB1 (0.33) | NFKB1TSHRALDH1A1CA12CA1 | |
| Ethylenediamine SCHEMBL4077816 | 0.94 | NFKB1 (0.33) | NFKB1TSHRALDH1A1CA12CA1 | |
| Ethylenediamine SCHEMBL3410087 | 0.94 | NFKB1 (0.33) | NFKB1TSHRALDH1A1CA12CA1 | |
| Ethylenediamine SCHEMBL987205 | 0.94 | NFKB1 (0.33) | NFKB1TSHRALDH1A1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 806 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12012362-B2 | Compositions and method to improve the aesthetics of calcium silicate-based cements and concretes | SOLIDIA TECHNOLOGIES, INC. (US) | 2024-06-18 | — | — | US | claimed |
| CN-116254059-B | Chemical mechanical polishing composition for edge polishing | 昂士特科技(深圳)有限公司 | 2024-01-23 | — | — | CN | claimed |
| US-11795247-B2 | Polyolefin dispersants and methods of making and using thereof | THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) | 2023-10-24 | — | — | US | claimed |
| CN-116574495-A | Biological enzyme-nano-composite sulfonate blocking remover, and preparation method and application thereof | 西安石油大油气科技有限公司 | 2023-08-11 | — | — | CN | claimed |
| US-11667573-B2 | Compositions and method to improve the strength development of calcium silicate-based cements and concretes | SOLIDIA TECHNOLOGIES, INC (US) | 2023-06-06 | — | — | US | claimed |
| EP-3368628-B1 | POLYURETHANE ADHESIVE COMPOSITION | DOW GLOBAL TECHNOLOGIES LLC (US) | 2022-01-26 | — | — | EP | claimed |
| CN-113480829-A | Low-viscosity epoxy/episulfide resin composition and epoxy/episulfide matrix resin | 牧世复合材料科技(苏州)有限公司 | 2021-10-08 | — | — | CN | claimed |
| CN-113480766-A | Preparation method of rapid curing fiber prepreg with incubation period | 牧世复合材料科技(苏州)有限公司 | 2021-10-08 | — | — | CN | claimed |
| US-20210189030-A1 | Polyolefin Dispersants and Methods of Making and Using Thereof | UNIVERSITY OF SOUTHERN MISSISSIPPI | 2021-06-24 | — | — | US | claimed |
| US-20210138437-A1 | METHODS OR PRODUCING CARBON DIOXIDE SORBENTS FOR INDOOR AIR QUALITY CONTROL | BASF MOBILE EMISSIONS CATALYSTS LLC | 2021-05-13 | — | — | US | claimed |
| EP-2464707-A1 | ORGANIC SALTS FOR REDUCING STONE PERMEABLITIES | BASF SE (DE) | 2012-06-20 | — | — | EP | claimed |
| US-20120142562-A1 | ORGANIC SALTS FOR REDUCING STONE PERMEABLITIES | BASF SE (DE) | 2012-06-07 | — | — | US | claimed |
| US-20120034492-A1 | ELECTROLESS COATED DISKS FOR HIGH TEMPERATURE APPLICATIONS AND METHODS OF MAKING THE SAME | COVENTYA, INC. (US) | 2012-02-09 | — | — | US | claimed |
| JP-2011527283-A | — | — | 2011-10-27 | — | — | JP | claimed |
| EP-2318323-A1 | COMPOSITION FOR REINFORCING HOLLOW GLASS AND PROTECTING SAME FROM SCRATCHING, CORRESPONDING TREATMENT METHODS AND RESULTING TREATED HOLLOW GLASS | SAINT-GOBAIN EMBALLAGE (FR) | 2011-05-11 | — | — | EP | claimed |
| WO-2011018257-A1 | ORGANIC SALTS FOR REDUCING STONE PERMEABLITIES | BASF SE (DE) | 2011-02-17 | — | — | WO | claimed |
| WO-2010004209-A1 | COMPOSITION FOR REINFORCING HOLLOW GLASS AND PROTECTING SAME FROM SCRATCHING, CORRESPONDING TREATMENT METHODS AND RESULTING TREATED HOLLOW GLASS | SAINT-GOBAIN EMBALLAGE (FR) | 2010-01-14 | — | — | WO | claimed |
| US-5512201-A | COMPRISING NITRIC ACID AQUEOUS SOLUTION WITH FERRIC IONS, A CHLORIDE ION SOURCE, METHYLSULFONIC ACID, ORGANIC AMINE AND SULFAMIC ACID | APPLIED CHEMICAL TECHNOLOGIES, INC. (US) | 1996-04-30 | — | — | US | claimed |
| US-4579670-A | Control of crosslinking reaction rate of aqueous fracturing fluids | BIG THREE INDUSTRIES, INC. (US) | 1986-04-01 | — | — | US | claimed |
| US-4486340-A | ENHANCED OIL RECOVERY; AMINE STABILIZER | UNION CARBIDE CORPORATION (US) | 1984-12-04 | — | — | US | claimed |