Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA3 | P07451 | 2/20 | 0.31 |
| ▸ | CA4 | P22748 | 2/20 | 0.31 |
| ▸ | CA6 | P23280 | 2/20 | 0.31 |
| ▸ | CA5A | P35218 | 2/20 | 0.31 |
| ▸ | CA7 | P43166 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL7621993 | 1.00 | NFKB1 (0.33) | NFKB1TSHRCA12CA1CA2 | |
| Ethylenediamine SCHEMBL989734 | 1.00 | NFKB1 (0.33) | NFKB1TSHRCA12CA1CA2 | |
| Ethylenediamine SCHEMBL371424 | 1.00 | NFKB1 (0.33) | NFKB1TSHRCA12CA1CA2 | |
| Ethylenediamine SCHEMBL220600 | 1.00 | — | — | |
| Ethylenediamine SCHEMBL10703973 | 1.00 | NFKB1 (0.33) | NFKB1TSHRCA12CA1CA2 | |
| Ethylenediamine SCHEMBL3410087 | 1.00 | NFKB1 (0.33) | NFKB1TSHRCA12CA1CA2 | |
| Ethylenediamine SCHEMBL19066603 | 1.00 | NFKB1 (0.33) | NFKB1TSHRCA12CA1CA2 | |
| Ethylenediamine SCHEMBL987205 | 1.00 | NFKB1 (0.33) | NFKB1TSHRCA12CA1CA2 | |
| Ethylenediamine SCHEMBL4077816 | 1.00 | NFKB1 (0.33) | NFKB1TSHRCA12CA1CA2 | |
| Ethylenediamine SCHEMBL642828 | 1.00 | NFKB1 (0.33) | NFKB1TSHRCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115124877-A | Use of carboxylic acid derivatives based on polyamines and/or polyalkanolamines in aqueous polyurethane dispersions | 赢创运营有限公司 | 2022-09-30 | — | — | CN | claimed |
| US-20190314756-A1 | METHOD AND SYSTEM FOR FILTERING FORMALDEHYDE FROM INOOR AIR | ENVERID SYSTEMS, INC. (US) | 2019-10-17 | — | — | US | claimed |
| US-20160228811-A1 | METHOD AND SYSTEM FOR FILTERING FORMALDEHYDE FROM INDOOR AIR | ENVERID SYSTEMS, INC. | 2016-08-11 | — | — | US | claimed |
| EP-3046648-A1 | METHOD AND SYSTEM FOR FILTERING FORMALDEHYDE FROM INDOOR AIR | Enverid Systems Inc. (US) | 2016-07-27 | — | — | EP | claimed |
| CN-115124877-A | Use of carboxylic acid derivatives based on polyamines and/or polyalkanolamines in aqueous polyurethane dispersions | 赢创运营有限公司 | 2022-09-30 | — | — | CN | disclosed |
| US-20190314756-A1 | METHOD AND SYSTEM FOR FILTERING FORMALDEHYDE FROM INOOR AIR | ENVERID SYSTEMS, INC. (US) | 2019-10-17 | — | — | US | disclosed |
| US-20190105597-A1 | REGENERABLE SORBENT CARTRIDGE ASSEMBLIES IN AIR SCRUBBERS | ENVERID SYSTEMS, INC. (US) | 2019-04-11 | — | — | US | disclosed |
| US-10143959-B2 | Regenerable sorbent cartridge assemblies in air scrubbers | ENVERID SYSTEMS, INC. (US) | 2018-12-04 | — | — | US | disclosed |
| US-9802148-B2 | Regenerable sorbent CO2 scrubber for submarine vessels | ENVERID SYSTEMS, INC. (US) | 2017-10-31 | — | — | US | disclosed |
| US-20170056812-A1 | REGENERABLE SORBENT CARTRIDGE ASSEMBLIES IN AIR SCRUBBERS | ENVERID SYSTEMS, INC. (US) | 2017-03-02 | — | — | US | disclosed |
| EP-3104955-A1 | REGENERABLE SORBENT CARTRIDGE ASSEMBLIES IN AIR SCRUBBERS | Enverid Systems Inc. (US) | 2016-12-21 | — | — | EP | disclosed |
| US-20160228811-A1 | METHOD AND SYSTEM FOR FILTERING FORMALDEHYDE FROM INDOOR AIR | ENVERID SYSTEMS, INC. | 2016-08-11 | — | — | US | disclosed |
| EP-3046648-A1 | METHOD AND SYSTEM FOR FILTERING FORMALDEHYDE FROM INDOOR AIR | Enverid Systems Inc. (US) | 2016-07-27 | — | — | EP | disclosed |
| EP-3001831-A1 | REGENERABLE SORBENT CO2 SCRUBBER FOR SUBMARINE VESSELS | Enverid Systems Inc. (US) | 2016-04-06 | — | — | EP | disclosed |
| US-20160082383-A1 | REGENERABLE SORBENT CO2 SCRUBBER FOR SUBMARINE VESSELS | ENVERID SYSTEMS, INC. (US) | 2016-03-24 | — | — | US | disclosed |
| WO-2015061262-A1 | MEHTODS AND FORMULATIONS FOR TREATING OIL-BASED FLUIDS | SOANE ENERGY, LLC (US) | 2015-04-30 | — | — | WO | disclosed |
| WO-2014176319-A1 | REGENERABLE SORBENT CO2 SCRUBBER FOR SUBMARINE VESSELS | ENVERID SYSTEMS, INC. (US) | 2014-10-30 | — | — | WO | disclosed |
| US-5772749-A | IMPROVING ADHESION BETWEEN ASPHALT AND AGGREGATE | WESTVACO CORPORATION (US) | 1998-06-30 | — | — | US | disclosed |
| US-5152909-A | Oxidation, corrosion resistance | TEXACO INC. (US) | 1992-10-06 | — | — | US | disclosed |