Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA3 | P07451 | 2/20 | 0.31 |
| ▸ | CA4 | P22748 | 2/20 | 0.31 |
| ▸ | CA6 | P23280 | 2/20 | 0.31 |
| ▸ | CA5A | P35218 | 2/20 | 0.31 |
| ▸ | CA7 | P43166 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL7621993 | 1.00 | NFKB1 (0.33) | NFKB1TSHRCA12CA1CA2 | |
| Ethylenediamine SCHEMBL989734 | 1.00 | NFKB1 (0.33) | NFKB1TSHRCA12CA1CA2 | |
| Ethylenediamine SCHEMBL371424 | 1.00 | NFKB1 (0.33) | NFKB1TSHRCA12CA1CA2 | |
| Ethylenediamine SCHEMBL220600 | 1.00 | — | — | |
| Ethylenediamine SCHEMBL10703973 | 1.00 | NFKB1 (0.33) | NFKB1TSHRCA12CA1CA2 | |
| Ethylenediamine SCHEMBL3410087 | 1.00 | NFKB1 (0.33) | NFKB1TSHRCA12CA1CA2 | |
| Ethylenediamine SCHEMBL19066603 | 1.00 | NFKB1 (0.33) | NFKB1TSHRCA12CA1CA2 | |
| Ethylenediamine SCHEMBL987205 | 1.00 | NFKB1 (0.33) | NFKB1TSHRCA12CA1CA2 | |
| Ethylenediamine SCHEMBL8667785 | 1.00 | NFKB1 (0.33) | NFKB1TSHRCA12CA1CA2 | |
| Ethylenediamine SCHEMBL642828 | 1.00 | NFKB1 (0.33) | NFKB1TSHRCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3027797-B1 | FORMALDEHYDE-FREE BINDER COMPOSITIONS AND METHODS OF MAKING COMPOSITES | JOHNS MANVILLE (US) | 2023-12-20 | — | — | EP | claimed |
| CN-110028170-B | Efficient scale inhibitor and application thereof | 四川文理学院 | 2022-01-25 | — | — | CN | claimed |
| CN-107297220-B | Vermicular mesoporous Al2O3Molecular sieve composite material and preparation method thereof | 武汉理工大学 | 2020-08-04 | — | — | CN | claimed |
| CN-107138127-B | Three-dimensional nano rod-shaped Al2O3@ molecular sieve shell-core composite material and preparation method thereof | 武汉理工大学 | 2020-06-19 | — | — | CN | claimed |
| US-9695311-B2 | Formaldehyde-free binder compositions and methods of making the binders | JOHNS MANVILLE (US) | 2017-07-04 | — | — | US | claimed |
| EP-3027797-A1 | FORMALDEHYDE-FREE BINDER COMPOSITIONS AND METHODS OF MAKING THE BINDERS | Johns Manville (US) | 2016-06-08 | — | — | EP | claimed |
| US-9034970-B2 | Curable fiberglass binder comprising salt of inorganic acid | JOHNS MANVILLE (US) | 2015-05-19 | — | — | US | claimed |
| WO-2015016873-A1 | FORMALDEHYDE-FREE BINDER COMPOSITIONS AND METHODS OF MAKING THE BINDERS | JOHNS MANVILLE (US) | 2015-02-05 | — | — | WO | claimed |
| US-20140027662-A1 | FORMALDEHYDE-FREE BINDER COMPOSITIONS AND METHODS OF MAKING THE BINDERS | JOHNS MANVILLE | 2014-01-30 | — | — | US | claimed |
| US-20130133548-A1 | CURABLE FIBERGLASS BINDER COMPRISING SALT OF INORGANIC ACID | SHOOSHTARI KIARASH ALAVI (US) | 2013-05-30 | — | — | US | claimed |
| EP-2033964-A2 | Corrosion inhibitor | Evonik Goldschmidt GmbH (DE) | 2009-03-11 | — | — | EP | claimed |
| US-20090053552-A1 | CORROSION INHIBITOR | EVONIK GOLDSCHMIDT GMBH (DE) | 2009-02-26 | — | — | US | claimed |
| CN-110028170-B | Efficient scale inhibitor and application thereof | 四川文理学院 | 2022-01-25 | — | — | CN | disclosed |
| CN-107297220-B | Vermicular mesoporous Al2O3Molecular sieve composite material and preparation method thereof | 武汉理工大学 | 2020-08-04 | — | — | CN | disclosed |
| CN-107138127-B | Three-dimensional nano rod-shaped Al2O3@ molecular sieve shell-core composite material and preparation method thereof | 武汉理工大学 | 2020-06-19 | — | — | CN | disclosed |
| EP-2033964-A2 | Corrosion inhibitor | Evonik Goldschmidt GmbH (DE) | 2009-03-11 | — | — | EP | disclosed |
| US-20090053552-A1 | CORROSION INHIBITOR | EVONIK GOLDSCHMIDT GMBH (DE) | 2009-02-26 | — | — | US | disclosed |
| US-4076505-A | REDUCING PYRITIC SULFUR CONTENT | MOBIL OIL CORPORATION (US) | 1978-02-28 | — | — | US | disclosed |