Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4844122 | 0.90 | HDAC6 (0.42) | HDAC6CHEK2ACHEHDAC3HDAC4 | |
| Trifluoroacetic Acid SCHEMBL4834051 | 0.87 | KDM4E (0.45) | HDAC6ACHEALDH1A1KDM4EHDAC3 | |
| Trifluoroacetic Acid SCHEMBL4838222 | 0.87 | ACHE (0.41) | HDAC6CHEK2ACHENPC1HDAC3 | |
| Trifluoroacetic Acid SCHEMBL4834242 | 0.87 | HDAC6 (0.40) | HDAC6CHEK2ACHEPDE3BPDE3A | |
| Trifluoroacetic Acid SCHEMBL4839525 | 0.85 | HDAC6 (0.49) | HDAC6CHEK2ACHEHDAC3HDAC4 | |
| Trifluoroacetic Acid SCHEMBL4843140 | 0.84 | HDAC6 (0.50) | HDAC6CHEK2ACHEHDAC3HDAC4 | |
| Trifluoroacetic Acid SCHEMBL4837229 | 0.81 | KDM4E (0.40) | HDAC6ALDH1A1KDM4EHDAC3HDAC4 | |
| SCHEMBL4845795 | 0.81 | ACHE (0.46) | HDAC6CHEK2ACHEHDAC3HDAC4 | |
| Trifluoroacetic Acid SCHEMBL4842876 | 0.81 | CHEK2 (0.45) | CHEK2NPC1ALDH1A1KDM4E | |
| Trifluoroacetic Acid SCHEMBL4843197 | 0.80 | TBK1 (0.51) | CHEK2ACHEALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7410966-B2 | Use of and some novel imidazopyridines | ASTRAZENECA AB (SE) | 2008-08-12 | — | — | US | disclosed |
| US-20050261333-A1 | Use of and some novel imidazopyridines | ASTRAZENECA A B (SE) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261333-A1 | Use of and some novel imidazopyridines | ITK, CSNK1A1, RPS6KA1 | HDAC6 981/4885CHEK2 309/4885ACHE 1390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.