SCHEMBL483900

SCHEMBL483900

Cc1ccnc(-c2cccc3c2oc2ccccc23)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.47
CCR1 P32246 1/20 0.44
CCR5 P51681 1/20 0.44
CCR8 P51685 1/20 0.44
NPC1 O15118 3/20 0.41
RAB9A P51151 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
PRKDC P78527 5/20 0.41
PIK3CD O00329 1/20 0.40
PIK3CB P42338 1/20 0.40
ALDH1A1 P00352 3/20 0.40
KDM4E B2RXH2 2/20 0.40
HPGD P15428 2/20 0.40
HSD17B10 Q99714 2/20 0.40
DRD4 P21917 1/20 0.40
TP53 P04637 1/20 0.40
PKM P14618 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
ATM Q13315 1/20 0.39
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29881874 1.00 ALOX5 (0.47) ALOX5CCR1CCR5CCR8NPC1
SCHEMBL21204223 0.94 MAOA (0.43) ALOX5CCR1CCR5CCR8NPC1
SCHEMBL26349380 0.90 CCR1 (0.43) ALOX5CCR1CCR5CCR8NPC1
SCHEMBL15696755 0.88 CCR1 (0.41) ALOX5CCR1CCR5CCR8NPC1
SCHEMBL15696757 0.87 CYP2A6 (0.43) ALOX5CCR1CCR5CCR8NPC1
SCHEMBL15696750 0.87 CYP2A6 (0.43) ALOX5CCR1CCR5CCR8NPC1
SCHEMBL24425927 0.85 CCR1 (0.39) ALOX5CCR1CCR5CCR8PRKDC
SCHEMBL26042989 0.85 ALOX5 (0.47) ALOX5NPC1RAB9APRKDCALDH1A1
SCHEMBL15696769 0.85 CYP2A6 (0.41) ALOX5CCR1CCR5CCR8NPC1
SCHEMBL15696768 0.84 SMN1; SMN2 (0.43) CCR1CCR5CCR8NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4701391-A2 HETEROLEPTIC IRIDIUM COMPLEX Universal Display Corporation (US) 2026-02-25 EP disclosed
US-12550604-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2026-02-10 US disclosed
EP-3643721-B1 HETEROLEPTIC IRIDIUM COMPLEX UNIVERSAL DISPLAY CORP (US) 2026-01-28 EP disclosed
US-20250338370-A1 HETEROLEPTIC IRIDIUM COMPLEXES AS DOPANTS UNIVERSAL DISPLAY CORPORATION (US) 2025-10-30 US disclosed
US-12448403-B2 Organometallic compound, organic light-emitting device including organometallic compound, and electronic apparatus including organic light-emitting device SAMSUNG ELECTRONICS CO., LTD. (KR) 2025-10-21 US disclosed
US-12408242-B2 Heteroleptic iridium complexes as dopants UNIVERSAL DISPLAY CORPORATION (US) 2025-09-02 US disclosed
US-12310229-B2 Organometallic compound, organic light-emitting device including organometallic compound, and electronic apparatus including organic light-emitting device SAMSUNG ELECTRONICS CO., LTD. (KR) 2025-05-20 US disclosed
US-20240180020-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-05-30 US disclosed
US-20240138251-A1 HETEROLEPTIC IRIDIUM COMPLEXES AS DOPANTS UNIVERSAL DISPLAY CORPORATION (US) 2024-04-25 US disclosed
US-11910701-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-02-20 US disclosed
US-20130026452-A1 HETEROLEPTIC IRIDIUM COMPLEXES AS DOPANTS UNIVERSAL DISPLAY CORPORATION (US) 2013-01-31 US disclosed
US-20130026452-A1 HETEROLEPTIC IRIDIUM COMPLEXES AS DOPANTS UNIVERSAL DISPLAY CORPORATION (US) 2013-01-31 US disclosed
EP-2551933-A1 Heteroleptic iridium complexes as dopants Universal Display Corporation (US) 2013-01-30 EP disclosed
EP-2551933-A1 Heteroleptic iridium complexes as dopants Universal Display Corporation (US) 2013-01-30 EP disclosed
EP-2411401-A1 HETEROLEPTIC IRIDIUM COMPLEX Universal Display Corporation (US) 2012-02-01 EP disclosed
US-20100244004-A1 HETEROLEPTIC IRIDIUM COMPLEX UNIVERSAL DISPLAY CORPORATION (US) 2010-09-30 US disclosed
US-20100244004-A1 HETEROLEPTIC IRIDIUM COMPLEX UNIVERSAL DISPLAY CORPORATION (US) 2010-09-30 US disclosed
US-20100244004-A1 HETEROLEPTIC IRIDIUM COMPLEX UNIVERSAL DISPLAY CORPORATION (US) 2010-09-30 US disclosed
WO-2010111175-A1 HETEROLEPTIC IRIDIUM COMPLEX UNIVERSAL DISPLAY CORPORATION (US) 2010-09-30 WO disclosed
WO-2010111175-A1 HETEROLEPTIC IRIDIUM COMPLEX UNIVERSAL DISPLAY CORPORATION (US) 2010-09-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11910701-B2 Organic electroluminescent materials and devices ICOSLG, PDCD1LG2, NECTIN4 ALOX5 1110/4885CCR1 3962/4885CCR5 2200/4885
US-12408242-B2 Heteroleptic iridium complexes as dopants JUND, DRD2, DRD1 ALOX5 324/4885CCR1 4248/4885CCR5 1635/4885
US-12310229-B2 Organometallic compound, organic light-emitting device including organometallic compound, and electronic apparatus including organic light-emitting device L1CAM, AP1M1, AP2M1 ALOX5 2795/4885CCR1 2331/4885CCR5 3409/4885
US-20250338370-A1 HETEROLEPTIC IRIDIUM COMPLEXES AS DOPANTS JUND, DRD2, DRD1 ALOX5 324/4885CCR1 4248/4885CCR5 1635/4885
US-20240180020-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, PDCD1LG2, NECTIN4 ALOX5 1110/4885CCR1 3962/4885CCR5 2200/4885
US-20240138251-A1 HETEROLEPTIC IRIDIUM COMPLEXES AS DOPANTS JUND, DRD2, DRD1 ALOX5 324/4885CCR1 4248/4885CCR5 1635/4885
US-20130026452-A1 HETEROLEPTIC IRIDIUM COMPLEXES AS DOPANTS JUND, DRD2, DRD1 ALOX5 324/4885CCR1 4248/4885CCR5 1635/4885
US-12448403-B2 Organometallic compound, organic light-emitting device including organometallic compound, and electronic apparatus including organic light-emitting device L1CAM, AP1M1, CHRM1 ALOX5 2912/4885CCR1 1489/4885CCR5 2365/4885
US-20100244004-A1 HETEROLEPTIC IRIDIUM COMPLEX DDT, ICOSLG, PDCD1LG2 ALOX5 680/4885CCR1 3836/4885CCR5 1536/4885
US-12550604-B2 Organic electroluminescent materials and devices ROS1, DNMT3A, PRDM9 ALOX5 3699/4885CCR1 3354/4885CCR5 2607/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.