Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 10/20 | 0.73 |
| ▸ | CES1 | P23141 | 10/20 | 0.73 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.73 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4836309 | 0.85 | CES1 (1.00) | FAAHCES1NCEH1 | |
| SCHEMBL2163056 | 0.85 | CES1 (1.00) | FAAHCES1NCEH1 | |
| SCHEMBL4837702 | 0.85 | CES1 (1.00) | FAAHCES1NCEH1 | |
| SCHEMBL4831663 | 0.85 | CES1 (1.00) | FAAHCES1NCEH1 | |
| SCHEMBL711249 | 0.81 | FAAH (0.74) | FAAHCES1 | |
| SCHEMBL1171686 | 0.79 | HDAC1 (0.55) | CES1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL2163471 | 0.79 | FAAH (1.00) | FAAHCES1NCEH1 | |
| SCHEMBL2163462 | 0.79 | FAAH (1.00) | FAAHCES1NCEH1 | |
| SCHEMBL4835098 | 0.79 | FAAH (1.00) | FAAHCES1NCEH1 | |
| SCHEMBL1171713 | 0.78 | HDAC1 (0.54) | CES1HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080096931-A1 | Oxadiazole ketone inhibitors of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-04-24 | — | — | US | claimed |
| US-7351724-B2 | Oxadiazole ketone inhibitors of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-04-01 | — | — | US | claimed |
| EP-1812427-A1 | OXADIAZOLE KETONE INHIBITORS OF FATTY ACID AMIDE HYDROLASE | The Scripps Research Institute (US) | 2007-08-01 | — | — | EP | claimed |
| US-20060100212-A1 | Oxadiazole ketone inhibitors of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2006-05-11 | — | — | US | claimed |
| WO-2006044617-A1 | OXADIAZOLE KETONE INHIBITORS OF FATTY ACID AMIDE HYDROLASE | THE SCRIPPS RESEARCH INSTITUTE (US) | 2006-04-27 | — | — | WO | claimed |
| US-20080096931-A1 | Oxadiazole ketone inhibitors of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-04-24 | — | — | US | disclosed |
| US-20080096931-A1 | Oxadiazole ketone inhibitors of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-04-24 | — | — | US | disclosed |
| US-20080096931-A1 | Oxadiazole ketone inhibitors of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-04-24 | — | — | US | disclosed |
| US-7351724-B2 | Oxadiazole ketone inhibitors of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-04-01 | — | — | US | disclosed |
| US-7351724-B2 | Oxadiazole ketone inhibitors of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-04-01 | — | — | US | disclosed |
| US-7351724-B2 | Oxadiazole ketone inhibitors of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-04-01 | — | — | US | disclosed |
| EP-1812427-A1 | OXADIAZOLE KETONE INHIBITORS OF FATTY ACID AMIDE HYDROLASE | The Scripps Research Institute (US) | 2007-08-01 | — | — | EP | disclosed |
| US-20060100212-A1 | Oxadiazole ketone inhibitors of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2006-05-11 | — | — | US | disclosed |
| WO-2006044617-A1 | OXADIAZOLE KETONE INHIBITORS OF FATTY ACID AMIDE HYDROLASE | THE SCRIPPS RESEARCH INSTITUTE (US) | 2006-04-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060100212-A1 | Oxadiazole ketone inhibitors of fatty acid amide hydrolase | FAAH, FAAH2, HCRTR2 | FAAH 1/4885CES1 60/4885NCEH1 22/4885 |
| US-20080096931-A1 | Oxadiazole ketone inhibitors of fatty acid amide hydrolase | FAAH, FAAH2, HCRTR2 | FAAH 1/4885CES1 60/4885NCEH1 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.