Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | TDO2 | P48775 | 2/20 | 0.37 |
| ▸ | IDO2 | Q6ZQW0 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29413799 | 0.80 | ADRB2 (0.43) | ACP3ADRB2ADRB1AOC3HIF1A | |
| SCHEMBL136204 | 0.80 | ADRB2 (0.43) | ACP3ADRB2ADRB1AOC3HIF1A | |
| SCHEMBL194130 | 0.78 | TSHR (0.50) | ACP3ADRB2ADRB1AOC3HIF1A | |
| SCHEMBL29397364 | 0.78 | TSHR (0.50) | ACP3ADRB2ADRB1AOC3HIF1A | |
| SCHEMBL31026111 | 0.78 | TSHR (0.50) | ACP3ADRB2ADRB1AOC3HIF1A | |
| SCHEMBL194129 | 0.78 | TSHR (0.50) | ACP3ADRB2ADRB1AOC3HIF1A | |
| SCHEMBL29501942 | 0.78 | TSHR (0.50) | ACP3ADRB2ADRB1AOC3HIF1A | |
| SCHEMBL1628799 | 0.78 | TSHR (0.50) | ACP3ADRB2ADRB1AOC3HIF1A | |
| SCHEMBL456765 | 0.77 | ADRB2 (0.47) | ACP3ADRB2ADRB1AOC3HIF1A | |
| SCHEMBL11606505 | 0.76 | TSHR (0.50) | ACP3ADRB2ADRB1AOC3HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7462731-B2 | Processes for the preparation of heterocyclic hydroxyamines and intermediates and catalysts for use therein | NPIL PHARMACEUTICALS (UK) LIMITED (GB) | 2008-12-09 | — | — | US | disclosed |
| US-20050272940-A1 | Processes for the preparation of heterocyclic hydroxyamines and intermediates and catalysts for use therein | AVECIA LIMITED (GB) | 2005-12-08 | — | — | US | disclosed |
| EP-1542985-A2 | PROCESSES FOR THE PREPARATION OF HETEROCYCLIC HYDROXYAMINES AND INTERMEDIATES AND CATALYSTS FOR USE THEREIN | Avecia Limited (GB) | 2005-06-22 | — | — | EP | disclosed |
| WO-2004024708-A2 | PROCESSES FOR THE PREPARATION OF HETEROCYCLIC HYDROXYAMINES AND INTERMEDIATES AND CATALYSTS FOR USE THEREIN | AVECIA LIMITED (GB) | 2004-03-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050272940-A1 | Processes for the preparation of heterocyclic hydroxyamines and intermediates and catalysts for use therein | OXGR1, HRH3, HRH4 | ACP3 4168/4885ADRB2 186/4885ADRB1 287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.