SCHEMBL4840158

SCHEMBL4840158

O=Cc1ccc2c(c1)c1ccccc1n2CC1CO1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHFR P00374 1/20 0.60
PTGER4 P35408 5/20 0.56
MAPT P10636 4/20 0.52
LMNA P02545 5/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
KDM4E B2RXH2 5/20 0.43
HTT P42858 2/20 0.43
POLB P06746 1/20 0.43
PKM P14618 1/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
SRC P12931 2/20 0.41
ALDH1A1 P00352 4/20 0.39
HPGD P15428 4/20 0.39
SMN1; SMN2 Q16637 4/20 0.39
TSHR P16473 2/20 0.39
USP2 O75604 1/20 0.39
CASP1 P29466 1/20 0.39
HSD17B10 Q99714 1/20 0.39
ALOX12 P18054 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5797985 0.84 PTGER4 (0.58) PTGER4KDM4EHTTPOLBPKM
SCHEMBL17938383 0.83 PTGER4 (0.56) PTGER4KDM4EHTTPOLBPKM
SCHEMBL29558375 0.82 DHFR (0.79) DHFRMAPTLMNAMEN1KMT2A
SCHEMBL15380515 0.82 DHFR (0.79) DHFRMAPTLMNAMEN1KMT2A
SCHEMBL15380522 0.82 DHFR (0.79) DHFRMAPTLMNAMEN1KMT2A
SCHEMBL30145441 0.82 DHFR (0.79) DHFRMAPTLMNAMEN1KMT2A
SCHEMBL409180 0.82 DHFR (0.79) DHFRMAPTLMNAMEN1KMT2A
SCHEMBL29558033 0.82 DHFR (0.79) DHFRMAPTLMNAMEN1KMT2A
SCHEMBL4779304 0.81 PTGER4 (0.54) PTGER4MAPTLMNAKDM4EHTT
SCHEMBL4839011 0.81 DHFR (0.64) DHFRPTGER4MAPTLMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7364825-B2 Charge transport materials having a nitrogen-containing-heterocycle hydrazone group SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-04-29 US disclosed
US-7291433-B2 Poly(hydrazone)-based charge transport materials SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-11-06 US disclosed
EP-1584987-B1 Poly(hydrazone)-based charge transport materials SAMSUNG ELECTRONICS CO LTD (KR) 2007-06-20 EP disclosed
US-20060177750-A1 Charge transport materials having a nitrogen-containing-heterocycle hydrazone group S-PRINTING SOLUTION CO., LTD. (KR) 2006-08-10 US disclosed
EP-1584987-A2 Poly(hydrazone)-based charge transport materials Samsung Electronics Co., Ltd. (KR) 2005-10-12 EP disclosed
US-20050221212-A1 Poly(hydrazone)-based charge transport materials S-PRINTING SOLUTION CO., LTD. (KR) 2005-10-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060177750-A1 Charge transport materials having a nitrogen-containing-heterocycle hydrazone group SLC1A2, SLC9B2, SLC6A19 DHFR 2490/4885PTGER4 1086/4885MAPT 4102/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.