SCHEMBL409180

SCHEMBL409180

c1ccc2c(c1)c1ccccc1n2CC1CO1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHFR P00374 1/20 0.79
MEN1 O00255 2/20 0.58
KMT2A Q03164 2/20 0.58
LMNA P02545 1/20 0.58
MAPT P10636 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.57
CYP1A2 P05177 2/20 0.52
CYP2C19 P33261 2/20 0.52
CYP19A1 P11511 1/20 0.45
TP53 P04637 2/20 0.45
HBB P68871 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
BACE1 P56817 2/20 0.44
KDM4E B2RXH2 2/20 0.42
TSHR P16473 2/20 0.41
SIGMAR1 Q99720 3/20 0.40
FABP3 P05413 1/20 0.40
FABP4 P15090 1/20 0.40
FABP5 Q01469 1/20 0.40
CA1 P00915 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30145441 1.00 DHFR (0.79) DHFRMEN1KMT2ALMNAMAPT
SCHEMBL29558033 1.00 DHFR (0.79) DHFRMEN1KMT2ALMNAMAPT
SCHEMBL15380522 1.00 DHFR (0.79) DHFRMEN1KMT2ALMNAMAPT
SCHEMBL15380515 1.00 DHFR (0.79) DHFRMEN1KMT2ALMNAMAPT
SCHEMBL29558375 1.00 DHFR (0.79) DHFRMEN1KMT2ALMNAMAPT
SCHEMBL4839011 0.88 DHFR (0.64) DHFRMEN1KMT2ALMNAMAPT
SCHEMBL13699647 0.85 DHFR (0.60) DHFRMEN1KMT2ALMNAMAPT
SCHEMBL412013 0.85 MAPT (0.85) DHFRMEN1KMT2ALMNAMAPT
SCHEMBL607994 0.85 DHFR (0.60) DHFRMEN1KMT2ALMNAMAPT
SCHEMBL28406140 0.85 DHFR (0.60) DHFRMEN1KMT2ALMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 296 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220112321-A1 HIGH REFRACTIVE INDEX MATERIALS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2022-04-14 US claimed
EP-3981806-A1 HIGH REFRACTIVE INDEX MATERIALS Rohm and Haas Electronic Materials LLC (US) 2022-04-13 EP claimed
CN-114316137-A High refractive index materials 罗门哈斯电子材料有限责任公司 2022-04-12 CN claimed
CN-1249520-C Optical medium for registration of holographic interferograms FILAUS HOLOTECH AS (SE) 2006-04-05 CN claimed
US-6593388-B2 Cationic polymers RENSSEALER POLYTECHNIC INSTITUTE 2003-07-15 US claimed
CN-1409831-A Optical medium for registration of holographic interferograms FILAUS HOLOTECH AS (SE) 2003-04-09 CN claimed
US-20020025991-A1 Oligomeric and polymeric photosensitizers RENSSELAER POLYTECHNIC INSTITUTE 2002-02-28 US claimed
US-20260139710-A1 BEARING DEVICE, METHOD OF MANUFACTURING BEARING DEVICE, HARD DISK DRIVE DEVICE, AND MOTOR MINEBEA MITSUMI INC (JP) 2026-05-21 US disclosed
CN-122062050-A Bearing device, method for manufacturing bearing device, hard disk drive device, and motor 美蓓亚三美株式会社 2026-05-19 CN disclosed
US-12624392-B2 Molecular array generation using photoresist 10X GENOMICS, INC. (US) 2026-05-12 US disclosed
US-12461444-B2 Sulfonium salt, photoacid generator, curable composition, and resist composition SAN-APRO LTD. (JP) 2025-11-04 US disclosed
EP-3909943-B1 SULFONIUM SALT, PHOTOACID GENERATOR, CURABLE COMPOSITION AND RESIST COMPOSITION SAN APRO LTD (JP) 2025-06-04 EP disclosed
WO-2025047236-A1 BEARING DEVICE, METHOD FOR MANUFACTURING BEARING DEVICE, HARD DISK DRIVE DEVICE, AND MOTOR ミネベアミツミ株式会社 2025-03-06 WO disclosed
EP-0000723-B1 POLYHYDROXY COMPOUNDS CONTAINING URETHANE-ARYL-SULFONIC ACID-HYDROXYALKYL ESTER GROUPS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS REACTION COMPONENTS FOR THE PREPARATION OF POLYURETHANE RESINS BAYER AG (DE) 1981-01-07 EP disclosed
US-4237250-A Polyurethanes containing aryl sulfonic acid alkyl ester groups BAYER AKTIENGESELLSCHAFT (DE) 1980-12-02 US disclosed
US-4211850-A Polyhydroxy compounds containing urethane aryl sulfonic acid hydroxyalkyl ester groups BAYER AKTIENGESELLSCHAFT (DE) 1980-07-08 US disclosed
US-4201852-A Polyurethanes based on modified polyisocyanates containing sulphonic acid ester groups and process for the production thereof BAYER AKTIENGESELLSCHAFT (DE) 1980-05-06 US disclosed
US-4189562-A Polyhydroxy compounds containing urethane aryl sulfonic acid hydroxyalkyl ester groups BAYER AKTIENGESELLSCHAFT (DE) 1980-02-19 US disclosed
EP-0000722-A1 Process for the preparation of polyurethanes containing arylsulfonic acid alkyl ester groups BAYER AG (DE) 1979-02-21 EP disclosed
EP-0000723-A1 Polyhydroxy compounds containing urethane-aryl-sulfonic acid-hydroxyalkyl ester groups, process for their preparation and their use as reaction components for the preparation of polyurethane resins BAYER AG (DE) 1979-02-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12624392-B2 Molecular array generation using photoresist POLL, LIG4, LIG3 DHFR 399/4885MEN1 4778/4885KMT2A 619/4885
US-20260139710-A1 BEARING DEVICE, METHOD OF MANUFACTURING BEARING DEVICE, HARD DISK DRIVE DEVICE, AND MOTOR ZW10, SOD1, EED DHFR 4073/4885MEN1 2897/4885KMT2A 1023/4885
US-12461444-B2 Sulfonium salt, photoacid generator, curable composition, and resist composition TIPRL, SPIN1, SPIN2B DHFR 2724/4885MEN1 1122/4885KMT2A 1624/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.