Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 13/20 | 0.43 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ADAMTS7 | Q9UKP4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4840605 | 0.93 | RORC (0.44) | RORCADAMTS5MMP8MMP3NR4A2 | |
| SCHEMBL4837122 | 0.91 | RORC (0.43) | RORCADAMTS5ADAMTS4MMP13MMP8 | |
| SCHEMBL4837344 | 0.91 | RORC (0.43) | RORCADAMTS5ADAMTS4MMP13MMP8 | |
| SCHEMBL4035496 | 0.91 | RORC (0.41) | RORCMMP8MMP3MMP1ADAM17 | |
| SCHEMBL4841404 | 0.90 | RORC (0.42) | RORCMMP8MMP3 | |
| SCHEMBL4839389 | 0.90 | RORC (0.39) | RORCADAMTS5MMP8MMP3ADAMTS7 | |
| SCHEMBL4840586 | 0.90 | RORC (0.40) | RORCADAMTS5MMP8MMP3ADAMTS7 | |
| SCHEMBL4845607 | 0.90 | RORC (0.42) | RORCADAMTS5ADAMTS4MMP13MMP8 | |
| SCHEMBL4843398 | 0.89 | RORC (0.40) | RORCMMP8MMP3 | |
| SCHEMBL4845108 | 0.89 | RORC (0.39) | RORCADAMTS5MMP8MMP3ADAMTS7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7465811-B2 | Indoline compounds | LABORATOIRES FOURNIER S.A. (FR) | 2008-12-16 | — | — | US | disclosed |
| US-20080119465-A1 | Novel Indoline Compounds | LABORATORIES FOURNIER S.A. (FR) | 2008-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119465-A1 | Novel Indoline Compounds | GPR119, INSR, IRS1 | RORC 1777/4885ADAMTS5 4240/4885ADAMTS4 4468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.