Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBX7 | O95931 | 1/20 | 0.33 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.33 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.33 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | GLI1 | P08151 | 1/20 | 0.31 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.31 |
| ▸ | WNT3A | P56704 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL281522 | 0.82 | SCN9A (0.33) | CBX7CDYL2CDYLCDY1; CDY1BSCN9A | |
| SCHEMBL281082 | 0.81 | SCN9A (0.47) | GAASCN9AALDH1A1 | |
| SCHEMBL281452 | 0.80 | CDYL (0.36) | CBX7CDYL2CDYLCDY1; CDY1BGAA | |
| SCHEMBL4168033 | 0.78 | SCN9A (0.55) | GAASCN9AALDH1A1 | |
| SCHEMBL484021 | 0.74 | TRPA1 (0.42) | GAAALDH1A1 | |
| SCHEMBL281912 | 0.71 | — | — | |
| SCHEMBL281679 | 0.68 | PTGDR2 (0.36) | GAASCN9ALMNA | |
| SCHEMBL281957 | 0.68 | ALDH1A1 (0.31) | SCN9AALDH1A1 | |
| SCHEMBL282052 | 0.68 | FABP4 (0.37) | SCN9AALDH1A1 | |
| SCHEMBL281967 | 0.68 | ALDH1A1 (0.37) | CBX7CDYL2CDYLCDY1; CDY1BSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888595-B1 | SPIRO-OXINDOLE COMPOUNDS AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC (CA) | 2012-02-01 | — | — | EP | disclosed |