Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CFTR | P13569 | 5/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ESRRA | P11474 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4841202 | 0.99 | THRA (0.46) | THRATHRBCFTRCYP1A2CYP2C9 | |
| SCHEMBL16726459 | 0.88 | THRA (0.60) | THRATHRBCFTRMAPTESRRA | |
| SCHEMBL25935035 | 0.88 | THRA (0.54) | THRATHRBCFTRCYP1A2CYP2C9 | |
| SCHEMBL25317633 | 0.86 | THRA (0.47) | THRATHRBCFTRCYP1A2CYP2C9 | |
| SCHEMBL27647625 | 0.86 | THRA (0.50) | THRATHRBCFTRCYP1A2CYP2C9 | |
| SCHEMBL27195871 | 0.84 | THRA (0.60) | THRATHRBCFTRALOX5APPDK2 | |
| SCHEMBL4838140 | 0.83 | MAPT (0.46) | MAPT | |
| SCHEMBL1941888 | 0.82 | CFTR (0.43) | THRATHRBCFTRCYP1A2CYP2C9 | |
| SCHEMBL1942565 | 0.82 | CYP1A2 (0.46) | THRATHRBCFTRCYP1A2CYP2C9 | |
| Hydrochloric Acid SCHEMBL4838135 | 0.82 | PARP10 (0.45) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7465811-B2 | Indoline compounds | LABORATOIRES FOURNIER S.A. (FR) | 2008-12-16 | — | — | US | disclosed |
| US-20080119465-A1 | Novel Indoline Compounds | LABORATORIES FOURNIER S.A. (FR) | 2008-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119465-A1 | Novel Indoline Compounds | GPR119, INSR, IRS1 | THRA 900/4885THRB 642/4885CFTR 4038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.