Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | NAAA | Q02083 | 1/20 | 0.51 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL10815854 | 1.00 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDNAAADNM1 | |
| Salicylic Acid SCHEMBL9814393 | 1.00 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDNAAADNM1 | |
| Salicylic Acid SCHEMBL10814962 | 1.00 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDNAAADNM1 | |
| Cetrimonium SCHEMBL4841411 | 1.00 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDNAAADNM1 | |
| Salicylic Acid SCHEMBL31588848 | 1.00 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDNAAADNM1 | |
| Cetrimonium SCHEMBL2165538 | 0.99 | ALDH1A1 (0.53) | ALDH1A1KDM4EHPGDNAAADNM1 | |
| Cetrimonium SCHEMBL3451127 | 0.99 | ALDH1A1 (0.53) | ALDH1A1KDM4EHPGDNAAADNM1 | |
| Cetrimonium SCHEMBL3451129 | 0.99 | ALDH1A1 (0.53) | ALDH1A1KDM4EHPGDNAAADNM1 | |
| Salicylic Acid SCHEMBL8016273 | 0.92 | KDM4E (0.46) | ALDH1A1KDM4EHPGDNAAAGAA | |
| Salicylic Acid SCHEMBL8016266 | 0.92 | KDM4E (0.46) | ALDH1A1KDM4EHPGDNAAAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115161000-B | Blocking remover for drilling fluid based on composite amino acid enzymatic hydrolysate and preparation and application methods thereof | 中石化石油工程技术服务有限公司 | 2024-05-03 | — | — | CN | claimed |
| US-7364599-B2 | Methods for increased removal of drag reducer additives from liquid hydrocarbon fuel | SOUTHWEST RESEARCH INSTITUTE (US) | 2008-04-29 | — | — | US | claimed |
| WO-2005087902-A1 | METHODS FOR INCREASED REMOVAL OF DRAG REDUCER ADDITIVES FROM LIQUID HYDROCARBON FUEL | SOUTHWEST RESEARCH INSTITUTE (US) | 2005-09-22 | — | — | WO | claimed |
| US-20040249233-A1 | Methods for increased removal of drag reducer additives from liquid hydrocarbon fuel | SOUTHWEST RESEARCH INSTITUTE | 2004-12-09 | — | — | US | claimed |
| EP-0092581-B1 | FRICTION REDUCTION USING A VISCOELASTIC SURFACTANT | THE DOW CHEMICAL COMPANY (US) | 1986-10-22 | — | — | EP | claimed |
| US-4615825-A | FOR FLOWING AQUEOUS LIQUIDS | THE DOW CHEMICAL COMPANY (US) | 1986-10-07 | — | — | US | claimed |
| EP-0092581-A4 | FRICTION REDUCTION USING A VISCOELASTIC SURFACTANT. | DOW CHEMICAL CO (US) | 1984-03-29 | — | — | EP | claimed |
| EP-0092581-A1 | FRICTION REDUCTION USING A VISCOELASTIC SURFACTANT. | DOW CHEMICAL CO (US) | 1983-11-02 | — | — | EP | claimed |
| WO-1983001583-A1 | FRICTION REDUCTION USING A VISCOELASTIC SURFACTANT | DOW CHEMICAL CO (US) | 1983-05-11 | — | — | WO | claimed |
| CN-120025478-A | Zwitterionic slow-release activator and preparation method and application thereof | 中国石油化工股份有限公司 | 2025-05-23 | — | — | CN | disclosed |
| CN-119552643-A | Geothermal drilling blocking removing liquid and blocking removing construction process | 延安大学 | 2025-03-04 | — | — | CN | disclosed |
| CN-115161000-B | Blocking remover for drilling fluid based on composite amino acid enzymatic hydrolysate and preparation and application methods thereof | 中石化石油工程技术服务有限公司 | 2024-05-03 | — | — | CN | disclosed |
| US-20180094105-A1 | AQUEOUS DISPERSION OF PARTICLES OF AT LEAST ONE THERMOPLASTIC POLYMER, METHOD FOR PREPARING AND APPLICATIONS THEREOF, ESPECIALLY FOR SIZING REINFORCING FIBRES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-04-05 | — | — | US | disclosed |
| US-7364599-B2 | Methods for increased removal of drag reducer additives from liquid hydrocarbon fuel | SOUTHWEST RESEARCH INSTITUTE (US) | 2008-04-29 | — | — | US | disclosed |
| EP-0149172-A1 | Fluorinated quaternary ammonium compounds, processes for their preparation and their use as drag reducing agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-07-24 | — | — | EP | disclosed |
| EP-0118089-A2 | Process for the mobility control of fracture, fissure or porous making flows | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-09-12 | — | — | EP | disclosed |
| EP-0092581-A4 | FRICTION REDUCTION USING A VISCOELASTIC SURFACTANT. | DOW CHEMICAL CO (US) | 1984-03-29 | — | — | EP | disclosed |
| EP-0097926-A1 | Quaternary ammonium salts and their use as drag reducing agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-01-11 | — | — | EP | disclosed |
| EP-0092581-A1 | FRICTION REDUCTION USING A VISCOELASTIC SURFACTANT. | DOW CHEMICAL CO (US) | 1983-11-02 | — | — | EP | disclosed |
| WO-1983001583-A1 | FRICTION REDUCTION USING A VISCOELASTIC SURFACTANT | DOW CHEMICAL CO (US) | 1983-05-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040249233-A1 | Methods for increased removal of drag reducer additives from liquid hydrocarbon fuel | GRHPR, BLVRB, DENR | ALDH1A1 1366/4885KDM4E 2591/4885HPGD 1049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.