Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 4/20 | 0.35 |
| ▸ | MMP9 | P14780 | 4/20 | 0.35 |
| ▸ | MMP8 | P22894 | 4/20 | 0.35 |
| ▸ | MMP13 | P45452 | 4/20 | 0.35 |
| ▸ | HPSE | Q9Y251 | 6/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5259949 | 0.91 | NPC1 (0.39) | NPC1RAB9AKMT2AMMP2MMP9 | |
| Trifluoroacetic Acid SCHEMBL4846619 | 0.84 | MMP2 (0.35) | NPC1RAB9AKMT2AMMP2MMP9 | |
| Trifluoroacetic Acid SCHEMBL4845870 | 0.84 | TAAR1 (0.41) | HPSE | |
| Trifluoroacetic Acid SCHEMBL4835219 | 0.83 | KMT2A (0.38) | NPC1RAB9AKMT2AMMP2MMP9 | |
| Trifluoroacetic Acid SCHEMBL4838725 | 0.82 | MMP2 (0.34) | NPC1RAB9AKMT2AMMP2MMP9 | |
| Trifluoroacetic Acid SCHEMBL4841657 | 0.82 | TAAR1 (0.41) | NPC1RAB9AKMT2AMMP2MMP9 | |
| Trifluoroacetic Acid SCHEMBL4845670 | 0.81 | FFAR1 (0.42) | HPSEFFAR1DGAT1 | |
| Trifluoroacetic Acid SCHEMBL5259763 | 0.81 | MMP2 (0.35) | NPC1RAB9AKMT2AMMP2MMP9 | |
| Trifluoroacetic Acid SCHEMBL4839090 | 0.81 | GPR6 (0.43) | MMP2MMP9MMP8MMP13FFAR1 | |
| Trifluoroacetic Acid SCHEMBL4837278 | 0.81 | HPSE (0.45) | NPC1RAB9AKMT2AHPSEFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7410966-B2 | Use of and some novel imidazopyridines | ASTRAZENECA AB (SE) | 2008-08-12 | — | — | US | disclosed |
| EP-1539759-B1 | NOVEL IMIDAZOPYRIDINES AND THEIR USE | ASTRAZENECA AB (SE) | 2007-08-15 | — | — | EP | disclosed |
| US-20050261333-A1 | Use of and some novel imidazopyridines | ASTRAZENECA A B (SE) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261333-A1 | Use of and some novel imidazopyridines | ITK, CSNK1A1, RPS6KA1 | NPC1 2655/4885RAB9A 1616/4885KMT2A 2697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.