Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | KLK1 | P06870 | 1/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 5/20 | 0.36 |
| ▸ | MMP9 | P14780 | 5/20 | 0.36 |
| ▸ | MMP8 | P22894 | 5/20 | 0.36 |
| ▸ | MMP13 | P45452 | 5/20 | 0.36 |
| ▸ | HPSE | Q9Y251 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4842422 | 0.91 | TAAR1 (0.47) | TAAR1FPR2KLK1KLK5MMP2 | |
| Trifluoroacetic Acid SCHEMBL4844134 | 0.84 | HPSE (0.36) | MMP2MMP9MMP8MMP13HPSE | |
| Trifluoroacetic Acid SCHEMBL4845870 | 0.84 | TAAR1 (0.41) | TAAR1HPSEFNTAFNTBPGGT1B | |
| Trifluoroacetic Acid SCHEMBL4838956 | 0.83 | SCD (0.42) | MMP2MMP9MMP8MMP13HPSE | |
| Trifluoroacetic Acid SCHEMBL4845670 | 0.83 | FFAR1 (0.42) | HPSEHDAC1 | |
| Trifluoroacetic Acid SCHEMBL5259763 | 0.83 | MMP2 (0.35) | MMP2MMP9MMP8MMP13HPSE | |
| Trifluoroacetic Acid SCHEMBL4841466 | 0.82 | NPC1 (0.35) | MMP2MMP9MMP8MMP13HPSE | |
| Trifluoroacetic Acid SCHEMBL4834343 | 0.82 | MAP3K8 (0.35) | MMP2MMP9MMP8MMP13HPSE | |
| Trifluoroacetic Acid SCHEMBL4838725 | 0.82 | MMP2 (0.34) | MMP2MMP9MMP8MMP13HPSE | |
| Trifluoroacetic Acid SCHEMBL4846619 | 0.82 | MMP2 (0.35) | MMP2MMP9MMP8MMP13HPSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7410966-B2 | Use of and some novel imidazopyridines | ASTRAZENECA AB (SE) | 2008-08-12 | — | — | US | disclosed |
| EP-1539759-B1 | NOVEL IMIDAZOPYRIDINES AND THEIR USE | ASTRAZENECA AB (SE) | 2007-08-15 | — | — | EP | disclosed |
| US-20050261333-A1 | Use of and some novel imidazopyridines | ASTRAZENECA A B (SE) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261333-A1 | Use of and some novel imidazopyridines | ITK, CSNK1A1, RPS6KA1 | TAAR1 2145/4885FPR2 3285/4885KLK1 1767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.