Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 11/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 4/20 | 0.33 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.32 |
| ▸ | WNT1 | P04628 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | CASR | P41180 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3963585 | 0.89 | ABCC9 (0.37) | CCR3HSD11B1SETD7WNT1GSK3B | |
| SCHEMBL4778945 | 0.84 | NPY5R (0.34) | BRD4SETD7WNT1GSK3BDYRK1A | |
| SCHEMBL3963810 | 0.79 | SETD7 (0.38) | CCR3HSD11B1SETD7 | |
| SCHEMBL3961355 | 0.73 | BDKRB1 (0.36) | SETD7 | |
| SCHEMBL4781352 | 0.73 | TERT (0.33) | SETD7 | |
| SCHEMBL3965157 | 0.71 | — | — | |
| SCHEMBL3965271 | 0.70 | DPP4 (0.31) | — | |
| SCHEMBL490182 | 0.68 | OPRD1 (0.40) | — | |
| SCHEMBL10235427 | 0.67 | SETD7 (0.41) | SETD7 | |
| SCHEMBL2628171 | 0.67 | SETD7 (0.46) | SETD7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910353-A1 | TRICYCLIC DELTA- OPIOID MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007030089-A1 | TRICYCLIC DELTA- OPIOID MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-03-15 | — | — | WO | disclosed |