Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 1.00 |
| ▸ | RAB9A | P51151 | 10/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 1.00 |
| ▸ | NPC1 | O15118 | 8/20 | 1.00 |
| ▸ | LMNA | P02545 | 5/20 | 1.00 |
| ▸ | PPARG | P37231 | 3/20 | 0.69 |
| ▸ | PPARD | Q03181 | 3/20 | 0.69 |
| ▸ | PPARA | Q07869 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.69 |
| ▸ | XDH | P47989 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | TP53 | P04637 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10564937 | 0.84 | RAB9A (0.72) | MAPTRAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL1675988 | 0.83 | RAB9A (0.71) | MAPTRAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL571576 | 0.83 | XDH (0.84) | MAPTRAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL13904574 | 0.83 | NPC1 (0.70) | MAPTRAB9ASMN1; SMN2NPC1LMNA | |
| Pseudobaptogenin SCHEMBL73016 | 0.81 | PPARG (1.00) | MAPTRAB9ASMN1; SMN2NPC1LMNA | |
| Derrustone SCHEMBL13657435 | 0.81 | SMN1; SMN2 (1.00) | MAPTRAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL29365787 | 0.81 | RAB9A (0.67) | MAPTRAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL571161 | 0.80 | RAB9A (1.00) | MAPTRAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL29482681 | 0.80 | RAB9A (1.00) | MAPTRAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL5504492 | 0.80 | MAPT (0.82) | MAPTRAB9ASMN1; SMN2NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009026657-A1 | FLAVONOID PPAR AGONISTS | THE UNIVERSITY OF SYDNEY (AU) | 2009-03-05 | — | — | WO | disclosed |
| US-7323621-B2 | Method of decreasing liquiritigenin-derived isoflavones relative to total isoflavones in plants and plants producing reduced ratio of liquiritigenin-derived isoflavones relative to total isoflavones | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-01-29 | — | — | US | disclosed |
| US-20040128714-A1 | Method of decreasing liquiritigenin-derived isoflavones relative to total isoflavones in plants and plants producing reduced ratio of liquiritigenin-derived isoflavones relative to total isoflavones | E.I. DU PONT DE NEMOURS AND COMPANY | 2004-07-01 | — | — | US | disclosed |