Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ESRRA | P11474 | 6/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.40 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.40 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.40 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7941025 | 0.80 | ALDH1A1 (0.56) | ALDH1A1GAAESRRANR1H4CYP3A4 | |
| SCHEMBL30176246 | 0.80 | ALDH1A1 (0.56) | ALDH1A1GAAESRRANR1H4CYP3A4 | |
| SCHEMBL28688212 | 0.80 | ALDH1A1 (0.60) | ALDH1A1GAAESRRATUBB4ATUBB | |
| SCHEMBL30040301 | 0.79 | NR4A1 (0.61) | ALDH1A1GAANR4A1TUBB4ATUBB | |
| SCHEMBL436522 | 0.79 | NR4A1 (0.61) | ALDH1A1GAANR4A1TUBB4ATUBB | |
| Hydroquinone SCHEMBL28293999 | 0.79 | ALDH1A1 (0.59) | ALDH1A1GAAESRRAALOX15LMNA | |
| SCHEMBL5381392 | 0.77 | NR4A1 (0.54) | ALDH1A1GAAESRRANR4A1NR1H4 | |
| SCHEMBL19809245 | 0.77 | NR4A1 (0.58) | ALDH1A1GAANR4A1MMP2MMP14 | |
| Hydrochloric Acid SCHEMBL10770715 | 0.77 | NR4A1 (0.58) | ALDH1A1GAANR4A1TUBB4ATUBB | |
| SCHEMBL716944 | 0.77 | NR4A1 (0.58) | ALDH1A1GAANR4A1MMP2MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7365231-B2 | Compound with antitumor activity and preparation method therefor | NATIONAL TAIWAN UNIVERSITY OF SCIENCE & TECHNOLOGY (TW) | 2008-04-29 | — | — | US | disclosed |
| US-20060241187-A1 | Compound with antitumor activity and preparation method therefor | NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (TW) | 2006-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060241187-A1 | Compound with antitumor activity and preparation method therefor | WEE1, WEE2, CYP51A1 | ALDH1A1 206/4885GAA 682/4885ESRRA 3481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.