Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.46 |
| ▸ | ENPP3 | O14638 | 4/20 | 0.39 |
| ▸ | ENPP1 | P22413 | 4/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 7/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2476540 | 0.85 | IRAK4 (0.40) | ENPP3ENPP1 | |
| SCHEMBL2164484 | 0.80 | GABRA1 (0.43) | PARP1ENPP3ENPP1 | |
| SCHEMBL28659326 | 0.76 | PARP1 (0.41) | PARP1ENPP3ENPP1FGFR1FGFR4 | |
| SCHEMBL23327801 | 0.73 | SLC22A12 (0.41) | PARP1ENPP3ENPP1SLC22A12SLC22A6 | |
| SCHEMBL4417290 | 0.72 | MKNK2 (0.41) | PARP1ENPP3ENPP1SLC22A12 | |
| SCHEMBL29665757 | 0.72 | MKNK2 (0.41) | PARP1ENPP3ENPP1SLC22A12 | |
| SCHEMBL23926503 | 0.72 | ENPP3 (0.47) | PARP1ENPP3ENPP1SLC22A12 | |
| SCHEMBL28139911 | 0.71 | ENPP3 (0.40) | PARP1ENPP3ENPP1FGFR1FGFR4 | |
| SCHEMBL30179105 | 0.70 | PDGFRB (0.41) | ENPP3ENPP1 | |
| SCHEMBL16495517 | 0.70 | PARP1 (0.39) | PARP1ENPP3ENPP1FGFR1FGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103739605-B | For detecting the developer of neurological disorder | 伊莱利利公司 | 2016-08-17 | — | — | CN | disclosed |
| EP-2550255-A1 | IMAGING AGENTS FOR DETECTING NEUROLOGICAL DISORDERS | Siemens Medical Solutions USA, Inc. (US) | 2013-01-30 | — | — | EP | disclosed |
| EP-2411057-A2 | IMAGING AGENTS FOR DETECTING NEUROLOGICAL DISORDERS | Siemens Medical Solutions USA, Inc. (US) | 2012-02-01 | — | — | EP | disclosed |
| WO-2011119565-A1 | IMAGING AGENTS FOR DETECTING NEUROLOGICAL DISORDERS | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2011-09-29 | — | — | WO | disclosed |
| WO-2010111303-A2 | IMAGING AGENTS FOR DETECTING NEUROLOGICAL DISORDERS | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2010-09-30 | — | — | WO | disclosed |