SCHEMBL2164484

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13262981	0.88	IRAK4 (0.44)	IRAK4
	SCHEMBL29056335	0.84	GABRA5 (0.41)	GABRA1GABRG2GABRB3GABRA5GABRA2
	SCHEMBL24450111	0.82	PIK3CA (0.40)	GABRG2GABRB3GABRA5PIK3CDABL1
	SCHEMBL30992116	0.81	ENPP3 (0.50)	GABRG2GABRB3GABRA5PIK3CDABL1
	SCHEMBL22130298	0.81	KDR (0.44)	PIK3CDABL1EGFRHCKSRC
	SCHEMBL18263905	0.81	PIK3CA (0.39)	GABRA1GABRG2GABRB3GABRA5GABRA2
	SCHEMBL13554542	0.81	ENPP3 (0.50)	GABRG2GABRB3GABRA5PIK3CDABL1
	SCHEMBL21292742	0.81	FGFR1 (0.46)	PIK3CDABL1EGFRHCKSRC
	SCHEMBL484170	0.80	PARP1 (0.46)	PARP1ENPP3ENPP1
	SCHEMBL23347080	0.80	KDR (0.39)	PIK3CDABL1EGFRHCKSRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.