SCHEMBL4841736

SCHEMBL4841736

C=CCc1nccnc1OC.O=[N+]([O-])CCc1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
HTT P42858 1/20 0.35
CYP11B1 P15538 4/20 0.33
CYP11B2 P19099 4/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
TXNRD1 Q16881 2/20 0.33
PKM P14618 1/20 0.33
CYP19A1 P11511 3/20 0.33
BCHE P06276 3/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
PIN1 Q13526 1/20 0.33
ATM Q13315 1/20 0.33
MAPT P10636 1/20 0.32
CNR2 P34972 1/20 0.32
CYP2D6 P10635 1/20 0.32
CHRM1 P11229 1/20 0.32
HRH1 P35367 1/20 0.32
KCNH2 Q12809 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL635872 0.76 ALDH1A1 (0.38) ALDH1A1HTTMEN1KMT2AMAPT
SCHEMBL264237 0.70 CNR1 (0.46) ALDH1A1CYP2C19
SCHEMBL13939867 0.70 CYP11B1 (0.41) CYP11B1CYP11B2CYP2D6CHRM1HRH1
Hydrogen Peroxide SCHEMBL28697848 0.68 CYP1A2 (0.47) ALDH1A1NPC1RAB9ACYP2C19
SCHEMBL1571379 0.68 LTA4H (0.46) ALDH1A1HTTMAPTCYP2D6CHRM1
SCHEMBL5140343 0.67 ALDH1A1 (0.40) ALDH1A1HTTMEN1KMT2ARAB9A
SCHEMBL11207496 0.64 CALM1 (0.48) ALDH1A1MEN1KMT2AMAPTCYP2C19
SCHEMBL509229 0.63 FFAR1 (0.58) ALDH1A1MEN1KMT2ABCHEMAPT
SCHEMBL490893 0.63 KCNJ1 (0.56) ALDH1A1NPC1RAB9AMAPTKCNH2
SCHEMBL28235247 0.62 CYP3A4 (0.43) ALDH1A1KMT2ANPC1RAB9ACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008009675-A2 USES OF 3,3'-DIHYDROXYISORENIERATENE AND RELATED CAROTINOIDS BASF SE (DE) 2008-01-24 WO disclosed