⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4844154 | 0.93 | ADRB1 (0.39) | — | |
| SCHEMBL4838349 | 0.88 | KDM1A (0.39) | — | |
| SCHEMBL5263244 | 0.86 | ALDH1A1 (0.49) | — | |
| SCHEMBL4838763 | 0.86 | MEN1 (0.42) | — | |
| SCHEMBL4844110 | 0.85 | AKT1 (0.44) | — | |
| SCHEMBL4842323 | 0.85 | ALDH1A1 (0.45) | — | |
| SCHEMBL4841793 | 0.85 | MAPT (0.41) | — | |
| SCHEMBL4841671 | 0.82 | CYP3A4 (0.43) | — | |
| SCHEMBL4843210 | 0.82 | ATM (0.50) | — | |
| Trifluoroacetic Acid SCHEMBL4845402 | 0.82 | MEN1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539759-B1 | NOVEL IMIDAZOPYRIDINES AND THEIR USE | ASTRAZENECA AB (SE) | 2007-08-15 | — | — | EP | claimed |
| US-20050261333-A1 | Use of and some novel imidazopyridines | ASTRAZENECA A B (SE) | 2005-11-24 | — | — | US | claimed |
| US-7410966-B2 | Use of and some novel imidazopyridines | ASTRAZENECA AB (SE) | 2008-08-12 | — | — | US | disclosed |
| EP-1539759-B1 | NOVEL IMIDAZOPYRIDINES AND THEIR USE | ASTRAZENECA AB (SE) | 2007-08-15 | — | — | EP | disclosed |
| US-20050261333-A1 | Use of and some novel imidazopyridines | ASTRAZENECA A B (SE) | 2005-11-24 | — | — | US | disclosed |