Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 5/20 | 0.47 |
| ▸ | CTSS | P25774 | 4/20 | 0.47 |
| ▸ | CTSB | P07858 | 4/20 | 0.47 |
| ▸ | CTSK | P43235 | 3/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | ECE1 | P42892 | 2/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4974719 | 0.85 | CASP3 (0.54) | CTSLCTSSCTSBCTSKSYK | |
| SCHEMBL3221956 | 0.81 | CTSL (0.52) | CTSLCTSSCTSBCTSKSYK | |
| SCHEMBL3221965 | 0.81 | CTSL (0.52) | CTSLCTSSCTSBCTSKSYK | |
| SCHEMBL2580714 | 0.81 | CTSL (0.52) | CTSLCTSSCTSBCTSKSYK | |
| SCHEMBL7373971 | 0.81 | CTSL (0.52) | CTSLCTSSCTSBCTSKSYK | |
| SCHEMBL220569 | 0.80 | CTSL (0.63) | CTSLCTSSCTSBCTSKELANE | |
| SCHEMBL1287168 | 0.80 | CTSL (0.63) | CTSLCTSSCTSBCTSKELANE | |
| SCHEMBL8671882 | 0.80 | CTSL (0.63) | CTSLCTSSCTSBCTSKELANE | |
| SCHEMBL2978398 | 0.80 | CTSL (0.63) | CTSLCTSSCTSBCTSKELANE | |
| SCHEMBL20529450 | 0.80 | CTRB1 (0.60) | CTSLCTSSCTSBCTSKATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008053157-A1 | AMINOHETEROARYL COMPOUNDS AS FOR THE TREATMENT OF DISEASES MEDIATED BY C-MET KINASE ACTIVITY | CHROMA THERAPEUTICS LTD. (GB) | 2008-05-08 | — | — | WO | disclosed |