SCHEMBL4844265

SCHEMBL4844265

O=CCC(=O)Nc1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.62
EPHX2 P34913 3/20 0.57
L3MBTL1 Q9Y468 2/20 0.56
MAPT P10636 3/20 0.53
HTT P42858 1/20 0.53
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
ALDH1A1 P00352 1/20 0.53
TP53 P04637 1/20 0.52
EPHX1 P07099 1/20 0.52
TSHR P16473 1/20 0.52
CDK9 P50750 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
CLK4 Q9HAZ1 1/20 0.52
KDM1A O60341 1/20 0.52
GAA P10253 1/20 0.52
SCN1A P35498 1/20 0.52
SCN2A Q99250 1/20 0.52
SCN3A Q9NY46 1/20 0.52
HDAC4 P56524 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28305020 0.86 MAOB (0.57) MAOBEPHX2L3MBTL1MAPTHTT
SCHEMBL20942407 0.86 ALDH1A1 (0.73) MAPTHTTMEN1KMT2AALDH1A1
SCHEMBL6578448 0.82 MAOB (0.61) MAOBEPHX2L3MBTL1MAPTHTT
SCHEMBL10393661 0.82 MEN1 (0.44) MAOBHTTMEN1KMT2AALDH1A1
SCHEMBL11220298 0.82 MAOB (0.61) MAOBEPHX2L3MBTL1MAPTHTT
SCHEMBL2576588 0.82 MAOB (0.61) MAOBEPHX2L3MBTL1MAPTHTT
SCHEMBL8473967 0.82 MAOB (0.61) MAOBEPHX2L3MBTL1MAPTHTT
SCHEMBL3163982 0.82 MAOB (0.61) MAOBEPHX2L3MBTL1MAPTHTT
SCHEMBL23660445 0.80 EPHX2 (0.53) MAOBEPHX2L3MBTL1MAPTHTT
SCHEMBL28404918 0.80 KMT2A (0.68) MAOBL3MBTL1MAPTHTTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2925771-B1 A PROCESS FOR THE PREPARATION OF SOLOMONAMIDE ANALOGUES COUNCIL SCIENT IND RES (IN) 2021-08-18 EP claimed
US-20150291659-A1 SOLOMONAMIDE ANALOGUE COMPOUNDS, PHARMACEUTICALS CONTAINING SOLOMONAMIDE ANALOGUE COMPOUNDS, AND PROCESSES FOR THE PREPARATION THEREOF COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2015-10-15 US claimed
EP-2925771-A1 A PROCESS FOR THE PREPARATION OF SOLOMONAMIDE ANALOGUES Council of Scientific & Industrial Research (IN) 2015-10-07 EP claimed
WO-2014083578-A1 A PROCESS FOR THE PREPARATION OF SOLOMONAMIDE ANALOGUES COUNCIL OF SCIENTIFIC & INDUSTRIAL RESERACH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN. OF SOC. ACT (ACT XXI OF 1860) (IN) 2014-06-05 WO claimed
CN-1315952-C Process for synthesizing polymethin cyanine compound containing indole ring TIANJIN COLLEGE OF SCIENCE AND (CN) 2007-05-16 CN claimed
CN-1532227-A Process for synthesizing polymethin cyanine compound containing indole ring 天津理工学院 2004-09-29 CN claimed
EP-1014186-A1 Photographic yellow dye-forming couplers EASTMAN KODAK COMPANY (US) 2000-06-28 EP claimed
EP-0777151-B1 Photographic element containing yellow dye-forming coupler comprising a dye light stability enhancing ballast and process EASTMAN KODAK CO (US) 2000-05-31 EP claimed
US-6040126-A OPEN CHAIN A-CARBONYL ACETANILIDE YELLOW DYE-FORMING COUPLER COMPOUND EASTMAN KODAK COMPANY (US) 2000-03-21 US claimed
US-5834167-A STABILITY; COLORFASTNESS EASTMAN KODAK COMPANY (US) 1998-11-10 US claimed
US-5677114-A Photographic element containing yellow dye-forming coupler comprising a dye light stability enhancing ballast and process EASTMAN KODAK COMPANY (US) 1997-10-14 US claimed
EP-0777151-A2 Photographic element containing yellow dye-forming coupler comprising a dye light stability enhancing ballast and process EASTMAN KODAK COMPANY (US) 1997-06-04 EP claimed
EP-0434807-A1 HETEROARYL-3-OXO-PROPANENITRILE DERIVATIVES USEFUL IN STIMULATING MYELOPOIESIS. ERBA CARLO SPA (IT) 1991-07-03 EP claimed
JP-58120251-A None JP disclosed
JP-9179259-A None JP disclosed
EP-2925771-B1 A PROCESS FOR THE PREPARATION OF SOLOMONAMIDE ANALOGUES COUNCIL SCIENT IND RES (IN) 2021-08-18 EP disclosed
US-4070337-A Bichromophoric benzotriazole-styrene ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1978-01-24 US disclosed
US-4070339-A Bichromophoric benzotriazole-styrene ester ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1978-01-24 US disclosed
US-4062800-A Bichromophoric benzoxazole-styrene ester and amide ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1977-12-13 US disclosed
US-3981884-A POLYMERS EASTMAN KODAK COMPANY (US) 1976-09-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150291659-A1 SOLOMONAMIDE ANALOGUE COMPOUNDS, PHARMACEUTICALS CONTAINING SOLOMONAMIDE ANALOGUE COMPOUNDS, AND PROCESSES FOR THE PREPARATION THEREOF CNR2, SRM, CNR1 MAOB 3445/4885EPHX2 3436/4885L3MBTL1 4793/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.