Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 8/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5257212 | 0.94 | MAPT (0.54) | HTR7MAPTKMT2AMAPK1L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL4844696 | 0.93 | CACNA1G (0.56) | HTR7MAPTKMT2AMAPK1L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL5258064 | 0.91 | KDM4E (0.55) | MAPTKMT2AMAPK1LMNAALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL4841832 | 0.91 | NPSR1 (0.39) | MAPTMAPK1L3MBTL1LMNAALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL5260279 | 0.89 | HSP90AB1 (0.51) | HTR7KMT2AABCB1CACNA1GKCNH2 | |
| Trifluoroacetic Acid SCHEMBL4844160 | 0.89 | ALDH1A1 (0.49) | MAPTKMT2AALDH1A1SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL4842213 | 0.89 | POLB (0.48) | HTR7MAPTKMT2AMAPK1L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL4843969 | 0.88 | NPSR1 (0.44) | HTR7MAPTKMT2AMAPK1ABCB1 | |
| Trifluoroacetic Acid SCHEMBL4845497 | 0.88 | ABCB1 (0.44) | MAPK1ABCB1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL4839418 | 0.88 | SCN1A (0.42) | KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7410966-B2 | Use of and some novel imidazopyridines | ASTRAZENECA AB (SE) | 2008-08-12 | — | — | US | disclosed |
| EP-1539759-B1 | NOVEL IMIDAZOPYRIDINES AND THEIR USE | ASTRAZENECA AB (SE) | 2007-08-15 | — | — | EP | disclosed |
| US-20050261333-A1 | Use of and some novel imidazopyridines | ASTRAZENECA A B (SE) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261333-A1 | Use of and some novel imidazopyridines | ITK, CSNK1A1, RPS6KA1 | HTR7 2515/4885MAPT 3669/4885KMT2A 2697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.