Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SCN1A | P35498 | 2/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4835082 | 0.93 | NPSR1 (0.45) | NPSR1MAPTALDH1A1L3MBTL1USP2 | |
| Trifluoroacetic Acid SCHEMBL4844160 | 0.92 | ALDH1A1 (0.49) | NPSR1MAPTALDH1A1SCN1ASCN5A | |
| Trifluoroacetic Acid SCHEMBL4842213 | 0.91 | POLB (0.48) | NPSR1MAPTL3MBTL1POLBUSP2 | |
| Trifluoroacetic Acid SCHEMBL4844675 | 0.91 | HTR7 (0.49) | MAPTALDH1A1L3MBTL1SMN1; SMN2MAPK1 | |
| Trifluoroacetic Acid SCHEMBL4839418 | 0.91 | SCN1A (0.42) | NPSR1SCN1ASCN5ASCN9AUSP2 | |
| Trifluoroacetic Acid SCHEMBL4843551 | 0.90 | ALDH1A1 (0.40) | NPSR1MAPTALDH1A1SCN1ASCN5A | |
| Trifluoroacetic Acid SCHEMBL4842369 | 0.89 | SCN1A (0.41) | SCN1ASCN5ASCN9A | |
| Trifluoroacetic Acid SCHEMBL4841950 | 0.88 | SCN1A (0.44) | SCN1ASCN5ASCN9A | |
| Trifluoroacetic Acid SCHEMBL5258064 | 0.88 | KDM4E (0.55) | NPSR1MAPTALDH1A1POLBUSP2 | |
| Trifluoroacetic Acid SCHEMBL4843969 | 0.88 | NPSR1 (0.44) | NPSR1MAPTUSP2SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7410966-B2 | Use of and some novel imidazopyridines | ASTRAZENECA AB (SE) | 2008-08-12 | — | — | US | disclosed |
| EP-1539759-B1 | NOVEL IMIDAZOPYRIDINES AND THEIR USE | ASTRAZENECA AB (SE) | 2007-08-15 | — | — | EP | disclosed |
| US-20050261333-A1 | Use of and some novel imidazopyridines | ASTRAZENECA A B (SE) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261333-A1 | Use of and some novel imidazopyridines | ITK, CSNK1A1, RPS6KA1 | NPSR1 1799/4885MAPT 3669/4885ALDH1A1 1489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.