Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.42 |
| ▸ | PPARG | P37231 | 7/20 | 0.42 |
| ▸ | PPARD | Q03181 | 7/20 | 0.42 |
| ▸ | PPARA | Q07869 | 7/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
| ▸ | TLR2 | O60603 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8014066 | 1.00 | ALDH1A1 (0.52) | ALDH1A1TSHRLMNANFKB1PMP22 | |
| SCHEMBL1930904 | 1.00 | ALDH1A1 (0.52) | ALDH1A1TSHRLMNANFKB1PMP22 | |
| SCHEMBL7562345 | 1.00 | ALDH1A1 (0.52) | ALDH1A1TSHRLMNANFKB1PMP22 | |
| SCHEMBL30864486 | 1.00 | ALDH1A1 (0.52) | ALDH1A1TSHRLMNANFKB1PMP22 | |
| SCHEMBL9842173 | 1.00 | ALDH1A1 (0.52) | ALDH1A1TSHRLMNANFKB1PMP22 | |
| SCHEMBL4855131 | 0.98 | ALDH1A1 (0.48) | ALDH1A1TSHRLMNANFKB1PMP22 | |
| SCHEMBL25278776 | 0.95 | ALDH1A1 (0.47) | ALDH1A1TSHRLMNANFKB1PMP22 | |
| SCHEMBL25288591 | 0.95 | ALDH1A1 (0.47) | ALDH1A1TSHRLMNANFKB1PMP22 | |
| SCHEMBL4590603 | 0.92 | ALDH1A1 (0.41) | ALDH1A1TSHRLMNANFKB1PMP22 | |
| SCHEMBL28489280 | 0.88 | ALDH1A1 (0.39) | ALDH1A1TSHRLMNANFKB1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7345037-B2 | Nitrosated and nitrosylated compounds and compositions and their use for treating respiratory disorders | NITROMED, INC. (US) | 2008-03-18 | — | — | US | disclosed |
| US-20070155781-A1 | Nitrosated and nitrosylated compounds and compositions and their use for treating respiratory disorders | ARBOR PHARMACEUTICALS, LLC | 2007-07-05 | — | — | US | disclosed |
| US-7160920-B2 | Nitrosated and nitrosylated compounds and compositions and their use for treating respiratory disorders | NITROMED, INC. (US) | 2007-01-09 | — | — | US | disclosed |
| US-20030199529-A1 | Nitrosated and nitrosylated compounds and compositions and their use for treating respiratory disorders | ARBOR PHARMACEUTICALS, LLC | 2003-10-23 | — | — | US | disclosed |
| US-6022714-A | Methods for attachment of a polynucleotide to a preselected material | GENETICS INSTITUTE (US) | 2000-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155781-A1 | Nitrosated and nitrosylated compounds and compositions and their use for treating respiratory disorders | EDNRA, NOS3, NOS1 | ALDH1A1 1293/4885TSHR 945/4885LMNA 1974/4885 |
| US-20030199529-A1 | Nitrosated and nitrosylated compounds and compositions and their use for treating respiratory disorders | NOS3, NOS1, EDNRA | ALDH1A1 1290/4885TSHR 951/4885LMNA 2065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.